Publications by authors named "Cristhian Camilo Rivera Caldon"
Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type.
Yulieth Cristina Bermúdez Burbano Angie Vanessa Caicedo Paz Cristhian Camilo Rivera Caldon Juan Sebastián Rodríguez Constain Gloria Inés Ávila Gonzáles
Rev Soc Bras Med Trop
July 2019
Introduction: Tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) is a disease caused by human T-cell lymphotropic virus type 1 (HTLV-I) that mainly infects CD4 T cells-for example, those of the CD4+CD25hiFOXP3+ [Treg] phenotype-where it inhibits forkhead box protein P3 (FOXP3) expression and promotes interferon-γ (IFN-γ) expression. However, the role it exerts on regulatory B cells (CD19+CD24hiCD38hi; Breg) is unknown.
Methods: The frequencies of Treg and Breg cells was evaluated and the Th1 profiles were assessed in TSP/HAM patients and healthy control subjects.