Publications by authors named "Crisci Alessandro"

The advanced-PRF+ (A-PRF+) is a platelet concentrate, showing a higher concentration of growth factors, an increased number of cells and looser structure of the fibrin clot than leukocyte-PRF. A high variability in the size of PRF associated with patients, haematological features and centrifugation protocols was reported. The aims of this study were to evaluate the feasibility of A-PRF+ production in the field and the correlation between haematological parameters, macroscopic and microscopic features in equine A-PRF+.

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Article Synopsis
  • * Seven diabetic patients with osteomyelitis and skin injuries were treated with A-PRF membranes after surgical cleaning, showing promising healing results over a six-month period.
  • * Out of the seven patients, six achieved significant healing of their skin lesions with no infections or relapses, suggesting A-PRF might be an effective therapy for this challenging condition.
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In this study, the use of fibrin rich in leukocytes and platelets (L-PRF) was explored to heal osteomyelitis ulcers in a diabetic foot. The goal was to standardize the utilization of L-PRF in patients with osteomyelitis to direct it for healing. L-PRF was obtained autologously from the peripheral blood of the diabetic patients ( = 3) having osteomyelitis and skin lesions for at least six months.

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