Publications by authors named "Cris M Ida"
An amplicon-based targeted next-generation sequencing (NGS) assay for the detection of gene fusions in sarcomas was developed, validated, and implemented. This assay can detect fusions in targeted regions of 138 genes and BCOR internal tandem duplications. This study reviews our experience with testing on the first 652 patients analyzed.
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- * The objective was to evaluate how individual BRAF alterations affect RAS dependency by analyzing genomic data from large cancer databases, focusing on coexisting alterations of RAS genes.
- * Results showed that certain BRAF alterations (class 1 and BRAF fusions) do not coexist with RAS or RAS regulatory gene alterations, indicating their independence, while class 2 BRAF alterations require further examination for similar patterns.