Publications by authors named "Cricket Nemkov"
Article Synopsis
- Tenofovir alafenamide (TAF) is shown to result in significantly higher levels of tenofovir-diphosphate (TFV-DP) in peripheral blood mononuclear cells (PBMCs) compared to tenofovir disoproxil fumarate (TDF) across different adherence levels.
- Two randomized studies were conducted with HIV-negative adults to compare the efficacy of TAF and TDF under varying daily dosing schedules.
- Results indicated that TAF consistently produced much higher levels of TFV-DP in PBMCs, suggesting it may offer enhanced potency and more forgiveness in dosing for preexposure prophylaxis compared to TDF.
