EFFICACY AND SAFETY OF BASAL INSULIN THERAPY IN ROMANIAN PATIENTS WITH TYPE 2 DIABETES IN REAL-LIFE SETTINGS: A SUB-GROUP ANALYSIS OF DUNE STUDY.

Context: Despite the available evidence showing the vital role of glycemic control in the management of type 2 diabetes, a significant proportion of patients are not achieving a good glycemic control.

Objective: Here we present the results of the Diabetes Unmet Need with basal insulin Evaluation (DUNE) study for patients enrolled in Romanian centers with the aim to describe the proportion of participants who achieved individualized HbA1c targets at 12 weeks following basal insulin therapy initiation.

Design: Prospective, observational study.

DIETARY PATTERNS AND THEIR ASSOCIATION WITH OBESITY: A CROSS-SECTIONAL STUDY.

Context: Scarce data on dietary habits in Eastern European countries is available and reports investigated individual food items and not dietary patterns in these populations.

Objective: To identify dietary patterns and to explore their association with obesity in a sample from Romanian population.

Design: Cross-sectional.

Sleep duration and body mass index: moderating effect of self-perceived stress and age. Results of a cross-sectional population-based study.

Purpose: The objective of this analysis was to assess whether the association between sleep duration and BMI and between sleep duration and waist circumference is moderated by age and self-perceived stress.

Methods: We analyzed data from 2034 participants enrolled in 2014 in the cross-sectional study Obesity in Romania Study-study of the prevalence of obesity and related risk factors in Romanian general population (ORO study).

Results: Interaction between sleep duration, self-perceived stress and age, with BMI as dependent variable, was statistically significant after adjustment for demographic and lifestyle factors (p value for interaction 0.

The relationship between the lipid structure of the hair and acute myocardial infarction.

In a group of patients with acute myocardial infarction (AMI) an evaluation of the derangements in lipid metabolism was carried out by analysing the fat structure of the hair (closely reflecting serum lipid variations). The data obtained reflects the real incidence of dyslipidemia associated with myocardial infarction. Through hair analysis, the evaluation in time (over weeks, months) of lipids metabolism under hypolipidemic therapy can be carried out without taking repeated samples.

[The measurement of proteins with major involvement in the immunological process in a group of 100 elderly patients].

Alpha-2-macroglobulin, alpha-1-antitrypsin and prealbumin were studied comparatively in 100 patients aged between 60 and 90 years and a series of patients aged 25-45 years. Prealbumin was low in both groups, alpha-2-macroglobulin was higher and alpha-1-antitrypsin was lower in the elderly patients.

[Factors with an anti-infectious role and immunologic involvement in a group of 100 elderly patients compared with a group of young patients].

From the study of the immunological aspects in the elderly it is noticed a marked decrease of: complement C3 fraction, and lysosime and the insignificant decrease of creatininephosphokinase.