Publications by authors named "Crandall R"

Article Synopsis
  • Cervical artery dissection (CeAD) is a leading cause of ischemic strokes in young adults, and this study explored the effects of intravenous thrombolysis (IVT) on patients with CeAD and stroke symptoms.
  • Analyzed data from the STOP-CAD study, it found that IVT significantly improved functional independence after 90 days in patients without increasing the risk of symptomatic intracranial hemorrhage.
  • The results suggest that IVT is a beneficial treatment for eligible patients with CeAD, aligning with current medical guidelines on its use.
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  • Uncertainty in restoring ecosystems, like southeastern USA pine savannas, can be reduced by studying factors affecting restoration success, particularly through experimental research.
  • The study focused on wiregrass (Aristida beyrichiana) and found that competition with native plants and the source of wiregrass seeds significantly impacted its growth and flowering in the first year.
  • Results showed that removing competition led to larger wiregrass plants with more flowers, and seeds from wetter sites generally produced more plants, indicating the importance of both seed source and competition in establishing successful wiregrass populations.
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  • PAMAM dendrimers, particularly the generation 4 (G4) version with a fully amine surface, are highly toxic to cells, prompting researchers to modify them for better biocompatibility by introducing neutral hydroxyl groups.
  • The modified G4-90/10 dendrimers, with a surface changing to 10% amine and 90% hydroxyl, show less toxicity and effective cellular uptake in various cell types, including neurons and stem cells.
  • Studies demonstrate that these dendrimers migrate within the brain after injection, with the G4 variety exhibiting more extensive movement patterns compared to G1 dendrimers, particularly in the anterior, posterior, and lateral directions, along with unique projections to cortical areas.
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Overstory trees serve multiple functions in grassy savannas. Past research has shown that understory species can vary along gradients of canopy cover and basal area in savannas. This variation is frequently associated with light availability but could also be related to other mechanisms, such as heterogeneity in soil and litter depth and fire intensity.

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Article Synopsis
  • Positive and negative interactions among species shape the assembly of communities, particularly in dryland plant ecosystems like southeastern U.S. savannas.
  • A study of longleaf pine and sandhill oaks revealed that higher oak densities significantly increased the survival and growth rates of longleaf pine seedlings, while lowest recruitment occurred under longleaf pine canopies.
  • The findings suggest that conserving and managing xeric oaks can enhance the recovery and sustainability of longleaf pine ecosystems, which are vital for global biodiversity.
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Students are required to complete supervised practice hours prior to becoming Registered Dietitians and Physician Assistants. Research suggests that environmental and social factors affect dietetic interns' diets during their internship, although these factors have not been studied among physician assistant interns. This cross-sectional study utilized an online survey to compare dietetic interns' ( = 81) and physician assistant interns' ( = 79) fruit and vegetable intake, food security, barriers to healthy eating, and empowerment for making healthy dietary choices during an internship.

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Premise: In frequently burned southeastern USA pine-grassland communities, wiregrass (Aristida stricta and A. beyrichiana) are dominant bunchgrasses whose flowers are infected during flowering by a smut fungus (Langdonia walkerae). We hypothesized that because prescribed fire timing affects wiregrass flowering patterns, it could affect smut incidence (occurrence of smut on plants) and severity of infection in inflorescences and spikelets.

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Background: Small, randomized trials of patients with cervical artery dissection showed conflicting results regarding optimal stroke prevention strategies. We aimed to compare outcomes in patients with cervical artery dissection treated with antiplatelets versus anticoagulation.

Methods: This is a multicenter observational retrospective international study (16 countries, 63 sites) that included patients with cervical artery dissection without major trauma.

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Wildlife conservation strategies focused on one season or population segment may fail to adequately protect populations, especially when a species' habitat preferences vary among seasons, age-classes, geographic regions, or other factors. Conservation of golden eagles (Aquila chrysaetos) is an example of such a complex scenario, in which the distribution, habitat use, and migratory strategies of this species of conservation concern vary by age-class, reproductive status, region, and season. Nonetheless, research aimed at mapping priority use areas to inform management of golden eagles in western North America has typically focused on territory-holding adults during the breeding period, largely to the exclusion of other seasons and life-history groups.

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Background: Circadian rhythm regulates many important biological functions in humans. The goal of this study is to explore the impact of day-to-day deviations in the sleep-wake cycle on nighttime blood pressure (BP) dipping and further examine whether the ethnic difference in day-to-day deviations in sleep patterns can explain the ethnic difference in nighttime BP dipping.

Methods: Twenty-four-hour ambulatory BP monitoring and 7-day accelerometer data were obtained from 365 adult participants (age range, 18.

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Hemlock woolly adelgid (HWA), Adelges tsugae Annand, is a major forest pest in the eastern United States responsible for killing millions of eastern hemlock, Tsuga canadensis (L.) Carrière and Carolina hemlock, T. caroliniana Engelmann.

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Spathius galinae is a larval parasitoid native to the Russian Far East that was approved for release in the United States in 2015 for biological control of the emerald ash borer (EAB), Agrilus planipennis, an invasive beetle from Asia responsible for widespread mortality of ash trees (Fraxinus spp.) in North America. From 2015 to 2017, 1,340-1,445 females of S.

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Introduction: Glycated hemoglobin can interfere with oxygen delivery and CO removal during exercise. Additionally, pancreatic insufficiency increases oxidative stress and exacerbates exercise intolerance in people with cystic fibrosis (PwCF). This investigation sought to test the hypotheses that elevated Hemoglobin A (HbA) can negatively affect exercise parameters in PwCF and that reductions in oxidative stress can improve tissue oxygenation in individuals with elevated HbA.

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The emerald ash borer (EAB), Agrilus planipennis Fairmaire, is the most destructive invasive pest on ash (Fraxinus spp.) in the United States. We determined whether ash trees injected with emamectin benzoate (EB) could protect untreated neighboring ash trees.

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Amyloidosis is characterized by depositing insoluble fibrillar proteins that misfold into beta-pleated sheets. This phenomenon occurs on a systemic or local level and may interfere with the function of various organs, including the heart, kidneys, and liver. Among those presenting with amyloidosis, hepatic, gastrointestinal, renal, cardiac, vitreous, and immunological involvement may occur.

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In the age of changing fire regimes, land managers often rely on prescribed burns to promote high diversity of herbaceous plants. Yet, little is known about how the timing of prescribed burns interacts with other ecological factors to maintain biodiversity while restoring fire-adapted ecosystems. We examined how timing of prescribed burns and removal of a dominant, early successional weedy plant yankeeweed () affect flower density and pollinator activity in an early-successional longleaf pine savanna restored from a timber plantation.

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Whole-body vibration (WBV) is an exercise mimetic that elicits beneficial metabolic effects. This study aims to investigate the effects of WBV amplitude on metabolic, inflammatory, and muscle oxygenation responses. Forty women and men were assigned to a high (HI; n = 20, Age: 31 ± 6 y) or a low-amplitude group (LO; n = 20, Age: 33 ± 6 y).

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Lead poisoning occurs worldwide in populations of predatory birds, but exposure rates and population impacts are known only from regional studies. We evaluated the lead exposure of 1210 bald and golden eagles from 38 US states across North America, including 620 live eagles. We detected unexpectedly high frequencies of lead poisoning of eagles, both chronic (46 to 47% of bald and golden eagles, as measured in bone) and acute (27 to 33% of bald eagles and 7 to 35% of golden eagles, as measured in liver, blood, and feathers).

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Article Synopsis
  • E-waste is increasing worldwide, leading to a study on harmful chemicals like dioxins and PCBs in female e-waste recyclers compared to non-recyclers in Vietnam.
  • Blood samples were analyzed, showing higher levels of toxic compounds in recyclers than in non-recyclers and some levels surpassed those found in the National Health and Nutrition Examination Surveys (NHANES).
  • The findings indicate significant exposure to specific dioxins and PCBs among recyclers, suggesting a need for intervention to reduce these harmful exposures.
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In the United States, the Bald and Golden Eagle Protection Act prohibits take of golden eagles (Aquila chrysaetos) unless authorized by permit, and stipulates that all permitted take must be sustainable. Golden eagles are unintentionally killed in conjunction with many lawful activities (e.g.

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For queer-spectrum students, college and university campuses are often sites of marginalization, discrimination, and/or harassment. Though such experiences are not singularly attributable to worldview, research highlights the role that religious identity plays in shaping individuals' perspectives on lesbian, gay, and bisexual (LGB) people. Absent from current scholarship, however, is insight into the ways in which interfaith experiences may influence those attitudes.

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Restoring fire regimes is a major goal of biodiversity conservation efforts in fire-prone ecosystems from which fire has been excluded. In the southeastern U.S.

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Background: Placenta accreta spectrum is most commonly diagnosed antenatally or at the time of delivery, but it may also present in the postpartum period.

Case: A 29-year-old primigravid patient without risk factors for placenta accreta spectrum had an uncomplicated vaginal birth with normal blood loss and delivery of an intact-appearing placenta. Five days postpartum, she was not lactating and uterine imaging to evaluate for retained products of conception was suspicious for placenta accreta spectrum.

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