Superior pedicle breast reduction techniques increase the risk of postoperative drainage.

Background: The most frequent complication after bilateral reduction mammoplasty (BRM) is the formation of seromas and hematomas. If a group of patients who are at increased risk of seroma and hematoma are identified, the use of drains in this group would be beneficial. We hypothesized that superior pedicle reductions would have increased postoperative drainage.

Completely autologous platelet gel in breast reduction surgery: a blinded, randomized, controlled trial.

Background: The objective of this study was to assess the effectiveness of topical application of completely autologous platelet gel during breast surgery to reduce postoperative wound drainage. An increasing number of surgical centers are using tissue sealants to reduce postoperative drainage and improve surgical outcomes. However, there is a paucity of randomized, double-blind, controlled trials assessing the efficacy of these agents.

The effect of epsilon aminocaproic acid on blood loss in patients who undergo primary total hip replacement: a pilot study.

Objective: To determine if the use of an antifibrinolytic agent (epsilon aminocaproic acid [EACA]) decreased perioperative and postoperative blood loss in patients who underwent total hip arthroplasty (THA).

Design: A prospective, double-blind, randomized, controlled clinical trial.

Setting: A university-affiliated tertiary care hospital with a large joint arthroplasty population.

Coronary artery bypass surgery with heparin-coated perfusion circuits and low-dose heparinization.

Objective: To evaluate the safety and efficacy of heparin-coated perfusion circuits with low-dose heparinization and centrifugal pumping compared with the standard method during coronary artery bypass grafting.

Design: Prospective, randomized, single-blind clinical trial.

Setting: A primary care institution.