Publications by authors named "Craig Clark"

Here we describe the data obtained by a successful proof-of-concept initiative to launch the first ocean color imager on board a CubeSat satellite and collect research-grade imagery at severalfold higher spatial resolution than any other ocean color satellite mission. The 3U CubeSat, named SeaHawk, flew at a nominal altitude of 585 km. Its ocean color sensor, HawkEye, collected 7,471 research-grade push-broom images of 230 × 780 km at best-in-class 130 × 130 m per pixel.

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The trapped-ion quantum charge-coupled device (QCCD) architecture is a leading candidate for advanced quantum information processing. In current QCCD implementations, imperfect ion transport and anomalous heating can excite ion motion during a calculation. To counteract this, intermediate cooling is necessary to maintain high-fidelity gate performance.

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Background Clinically relevant aortic dilatation (>40 mm) and increased cardiovascular risk are common among retired professional American-style football athletes. Among younger athletes, the effect of American-style football participation on aortic size is incompletely understood. We sought to determine changes in aortic root (AR) size and associated cardiovascular phenotypes across the collegiate career.

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Background Ventricular-arterial (VA) coupling is defined as the ratio between arterial elastance (EA) and left ventricular elastance (ELV). VA uncoupling, as occurs in hypertensive heart disease, is associated with adverse outcomes. This study sought to determine the relationship between American football (AF)-associated hypertension and VA uncoupling.

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We implement a 2-qubit entangling Mølmer-Sørensen interaction by transporting two cotrapped ^{40}Ca^{+} ions through a stationary, bichromatic optical beam within a surface-electrode Paul trap. We describe a procedure for achieving a constant Doppler shift during the transport, which uses fine temporal adjustment of the moving confinement potential. The fixed interaction duration of the ions transported through the laser beam as well as the dynamically changing ac Stark shift require alterations to the calibration procedures used for a stationary gate.

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Entanglement generation in trapped-ion systems has relied thus far on two distinct but related geometric phase gate techniques: Mølmer-Sørensen and light-shift gates. We recently proposed a variant of the light-shift scheme where the qubit levels are separated by an optical frequency [B. C.

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Objectives: American-style football (ASF) athletes are at risk for the development of concentric left ventricular hypertrophy (C-LVH), an established cardiovascular risk factor in the general population. We sought to address whether black race is associated with acquired C-LVH in collegiate ASF athletes.

Methods: Collegiate ASF athletes from two National Collegiate Athletic Association Division-I programmes were recruited as freshmen between 2014 and 2019 and analysed over 3 years.

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The COVID-19 pandemic caused by the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effort to achieve sufficient diagnostic testing capability for identifying infected individuals. In this study, we report the analytical and clinical performance characteristics of a new, high-throughput, fully automated nucleic acid amplification test system for the detection of SARS-CoV-2. The assay utilizes target capture, transcription-mediated amplification, and acridinium ester-labeled probe chemistry on the automated Panther system to directly amplify and detect two separate target sequences in the open reading frame 1ab (ORF1ab) region of the SARS-CoV-2 RNA genome.

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Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with adverse cardiovascular outcomes and reportedly overused in American-style football (ASF). However, assessment of ASF NSAID use in the context of cardiovascular risk has not been performed. We sought to characterize NSAID use patterns and the association with cardiovascular risk in a diverse cohort of high school and collegiate ASF athletes.

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Infectious vaginitis due to bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and accounts for a significant proportion of all gynecologic visits in the United States. A prospective multicenter clinical study was conducted to validate the performance of two new diagnostic transcription-mediated amplification nucleic acid amplification tests (NAATs) for diagnosis of BV, VVC, and trichomoniasis. Patient- and clinician-collected vaginal-swab samples obtained from women with symptoms of vaginitis were tested with the Aptima BV and Aptima vaginitis (CV/TV) assays.

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Importance: Former US football athletes are at increased risk of cardiovascular (CV) morbidity and mortality compared with the general population and other professional athletes. However, responsible maladaptive CV phenotypes have not been fully characterized.

Objective: To address the emergence and progression of multiple independent factors associated with CV risk across serial years of collegiate US football participation.

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After its inadvertent introduction to Guam, the brown tree snake (Boiga irregularis, BTS) extirpated most of the island's native terrestrial vertebrates, presented a health hazard to small children, and had considerable economic ramifications. Management of BTS is aimed at a number of objectives, the foremost of which has been to deter its dispersal from Guam to other locations. Further objectives include reclaiming areas on Guam as snake-free for reintroduction of native wildlife, to protect small sensitive sites on Guam from BTS intrusion (e.

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Purpose: American-style football (ASF) participation rates in the United States are highest among high school (HS) athletes. This study sought to compare the cardiovascular response to HS versus collegiate ASF participation.

Methods: The ASF participants (HS, n = 61; collegiate, n = 87) were studied at preseason and postseason time points with echocardiography and applanation tonometry.

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This study sought to determine the cardiovascular physiologic correlates of sleep-disordered breathing (SDB) in American-style football (ASF) participants using echocardiography, vascular applanation tonometry, and peripheral arterial tonometry. Forty collegiate ASF participants were analyzed at pre- and postseason time points with echocardiography and vascular applanation tonometry. WatchPAT (inclusive of peripheral arterial tonometry) used to assess for SDB was then performed at the postseason time point.

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Pulmonary hypertension from left heart disease (PH-LHD) is the most common form of PH, defined as mean pulmonary artery pressure ≥25 mm Hg and pulmonary artery wedge pressure ≥15 mm Hg. PH-LHD development is associated with more severe left-sided disease and its presence portends a poor prognosis, particularly once right ventricular failure develops. Treatment remains focused on the underlying LHD and despite initial enthusiasm for PH-specific therapies, most studies have been disappointing and their routine clinical use cannot be recommended.

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Background: In patients with atrial fibrillation or flutter, a left atrial appendage ejection velocity measured via transesophageal echocardiography equal to or less than 40 cm/sec has been shown to correlate with an increased risk of developing left atrial appendage thrombus while velocities greater than 40 cm/sec are at lower risk. The CHADS2 and CHA2DS2-VASc scores calculated from clinical variables have been developed to risk stratify patients with atrial fibrillation/flutter in regard to the need for anticoagulation. This study was designed to assess whether a relationship exists between left atrial appendage ejection velocities and the respective CHADS2 and CHA2DS2-VASc scores, and whether this relationship is affected by the presence of atrial fibrillation or atrial flutter.

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The masses of single molecular ions are nondestructively measured by cotrapping the ion of interest with a laser-cooled atomic ion, (40)Ca(+). Measurement of the resolved sidebands of a dipole forbidden transition on the atomic ion reveals the normal-mode frequencies of the two ion system. The mass of two molecular ions, (40)CaH(+) and (40)Ca(16)O(+), are then determined from the normal-mode frequencies.

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We present the infrared spectra of H3O2(-) and D3O2(-) calculated using MP2 direct molecular dynamics approach at temperatures of 100 and 300 K. The spectral peaks were assigned using the normal-mode analysis, instantaneous normal-mode analysis, isotopic substitution, polarized infrared absorptions, and analysis of the position-position correlation function. Our results predict the bridging hydrogen stretch between 600 and 900 cm(-1) and bridging hydrogen bend vibrations between 1250 and 1650 cm(-1).

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The development of maize (Zea mays L.) varieties as factories of pharmaceutical and industrial compounds has renewed interest in controlling pollen dispersal. The objective of this study was to compare gene flow into maize fields of different local pollen densities under the same environmental conditions.

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Background: Prostate cancer gene 3 (PCA3) encodes a prostate-specific mRNA that has shown promise as a prostate cancer diagnostic tool. This report describes the characterization of a prototype quantitative PCA3-based test for whole urine.

Methods: Whole-urine specimens were collected after digital rectal examination from 3 groups: men scheduled for prostate biopsy (n = 70), healthy men (<45 years of age with no known prostate cancer risk factors; n = 52), and men who had undergone radical prostatectomy (n = 21).

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