Publications by authors named "Coxon D"

Aim: The aim of this review was to explore the experiences of pregnant women and birthing people with higher weight bodies, to understand the extent to which weight stigma impacted their maternity care.

Methods: We performed a systematic search of seven databases (CINAHL plus, Medline, Social Sciences Full Text [SSFT], International Bibliography of Social Sciences [IBSS], PsychINFO, Maternity and Infant Care [MIC], NIHR Journals Library, EThOS) using the Setting, Perspective, Intervention, Comparison, Evaluation (SPICE) framework search strategy and pre-defined inclusion and exclusion criteria. Included studies underwent a critical appraisal and data richness assessment.

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The perturbed free induction decay (PFID) observed in ultrafast infrared spectroscopy was used to unveil the rates at which different vibrational modes of the same atomic-scale defect can interact with their environment. The N_{3}VH^{0} defect in diamond provided a model system, allowing a comparison of stretch and bend vibrational modes within different crystal lattice environments. The observed bend mode (first overtone) exhibited dephasing times T_{2}=2.

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Light-to-heat conversion materials generate great interest due to their widespread applications, notable exemplars being solar energy harvesting and photoprotection. Another more recently identified potential application for such materials is in molecular heaters for agriculture, whose function is to protect crops from extreme cold weather and extend both the growing season and the geographic areas capable of supporting growth, all of which could help reduce food security challenges. To address this demand, a new series of phenolic-based barbituric absorbers of ultraviolet (UV) radiation has been designed and synthesised in a sustainable manner.

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The sparsity of efficient commercial ultraviolet-A (UV-A) filters is a major challenge toward developing effective broadband sunscreens with minimal human- and eco-toxicity. To combat this, we have designed a new class of Meldrum-based phenolic UV-A filters. We explore the ultrafast photodynamics of coumaryl Meldrum, CMe, and sinapyl Meldrum (SMe), both in an industry-standard emollient and on a synthetic skin mimic, using femtosecond transient electronic and vibrational absorption spectroscopies and computational simulations.

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With the growing concern regarding commercially available ultraviolet (UV) filters damaging the environment, there is an urgent need to discover new UV filters. A family of molecules called mycosporines and mycosporine-like amino acids (referred to as MAAs collectively) are synthesized by cyanobacteria, fungi and algae and act as the natural UV filters for these organisms. Mycosporines are formed of a cyclohexenone core structure while mycosporine-like amino acids are formed of a cyclohexenimine core structure.

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Article Synopsis
  • Atomic-scale defects in crystalline materials like diamond significantly influence their optoelectronic performance, with the NVH defect being a key player for quantum technologies.
  • The NVH defect consists of a lattice vacancy involving nitrogen impurities and a hydrogen atom, which leads to distinct absorption features in the mid-infrared range.
  • The study employs advanced infrared absorption spectroscopy to investigate the vibrational dynamics of the NVH defect, revealing energy relaxation pathways and enhancing our understanding of atomic-scale defects for future applications.
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Background: Over recent years there has been a growth in cancer early diagnosis (ED) research, which requires valid measurement of routes to diagnosis and diagnostic intervals. The Aarhus Statement, published in 2012, provided methodological guidance to generate valid data on these key pre-diagnostic measures. However, there is still a wide variety of measuring instruments of varying quality in published research.

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Article Synopsis
  • Middle-income countries, like Brazil, are struggling to provide adequate health care for individuals with multimorbidity, defined as having two or more chronic health conditions.
  • A study involving over 60,000 adults found that 24.2% of the population had multimorbidity, with higher rates among women, older adults, and those with lower education levels.
  • The research identified three common patterns of multimorbidity: "cardio-metabolic," "musculoskeletal-mental," and "respiratory," and emphasizes the need for a national plan to better address the health care needs of this group.
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Objectives: Some patients spend years with painful osteoarthritis without consulting for it, including times when they are experiencing persistent severe pain and disability. Beliefs about osteoarthritis and what primary care has to offer may influence the decision to consult but their relative importance has seldom been quantified. We sought to investigate the relative importance of perceived service-related and clinical need attributes in the decision to consult a primary care physician for painful osteoarthritis.

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The methyl esters of 4 individual positional isomers of hydroperoxides, 2 positional isomers of hydroperoxy cyclic peroxides and a 9,16-dihydroperoxide were prepared by autoxidation of methyl linolenate and separated by preparative high pressure liquid chromatography. Isolated hydroperoxide isomers were thermally decomposed and the resulting volatile components analyzed. Each hydroperoxide or hydroperoxy cyclic peroxide isomer yielded characteristic volatile products.

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A radioimmunoassay for solanidine, the major hydrolysis product of potato glycoalkaloids, has been established and validated for application to human plasma. All 34 samples of human plasma tested contained solanidine, with a mean of 1.27 +/- 0.

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The lipid content of seed from a set of isogenic lines for the R a : r a locus has been determined; the results show that this locus as well as affecting the starch, sugar and storage protein content and composition, also has a marked effect on the lipid content of the seed. Genotypes having different combinations of alleles at the r a and r b loci have also been examined; an r a r a r b r b , genotype had 5.57% purified total lipid in its seed - a more than 2-fold increase over that found in the round-seeded varieties (R a R a R b R b ) usually grown for the dry sed crop.

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