Acute adolescent menorrhagia.

Acute menorrhagia in adolescence is a much underestimated clinical problem, often requiring urgent medical intervention. In a 9-year case review between January, 1971, and January, 1980, we looked at all admissions to a children's hospital for acute menorrhagia, where genital tract pathology had been excluded. A primary coagulation disorder was found in almost 20% of these 59 patients.

Clinical investigation of the effects of dentifrices on dentin wear at the cementoenamel junction.

A two-year clinical study was conducted in vivo to assess the dentin wear caused by dentifrices; results were correlated and compared with those obtained in vitro.

The Anti-Coronary Club: 1957 to 1972.

The Diet and Coronary Heart Disease Study Project, known as the Anti-Coronary Club, was established by the New York City Department of Health, Bureau of Nutrition in June 1957. The major goals were: 1) to develop an acceptable experimental diet capable of reducing serum cholesterol in ambulatory middle-aged men; and 2) to test the hypothesis that a reduction in serum cholesterol is associated with a modified diet and a reduced incidence of coronary heart disease development. The Prudent Diet was developed to provide a way of eating consistent with the American dietary pattern, avoiding an excess of empty calories, saturated fat, and food cholesterol.

Testing therapeutic measures for controlling chronic gingivitis in man: the results of two studies.

A previous paper described a suggested protocol which could be used for testing therapeutic measures. In this paper the protocol has been used as a basis for testing experimental toothpastes over short and medium periods of time. The effects on plaque and gingivitis of a chlorhexidine paste used for 4 weeks, and of two other experimental products used over 8 weeks, have been investigated.

Testing therapeutic measures for controlling chronic gingivitis in man: a suggested protocol.

A protocol is presented for the clinical evaluation of agents used to control chronic gingivtis in man. Assessment is divided into three phases of increasing duration which are the initial screening of products over 1 month, the main gingivitis trial lasting at least 6 months and judging the effect of the product in preventing periodontitis which is extended for at least 3 years. The advances in data processing have made it possible to collect information separately on the three parameters of gingival inflammation.