Pediatric differentiated thyroid carcinoma: trends in practice and outcomes over 40 years at a single tertiary care institution.

Background: This study aims to analyze changes in characteristics, practice and outcomes of pediatric differentiated thyroid cancer (DTC) at our tertiary care institution.

Methods: Patients <21 years of age diagnosed between 1973 and 2013 were identified. Clinicopathological data, treatment and outcomes were obtained by a retrospective review.

Use of palliative care and hospice among surgical and medical specialties in the Veterans Health Administration.

Importance: Many hospitals have undertaken initiatives to improve care during the end of life, recognizing that some individuals have unique needs that are often not met in acute inpatient care settings. Studies of surgical patients have shown this population to receive palliative care at reduced rates in comparison with medical patients.

Objective: To determine differences in the use of palliative care and hospice between surgical and medical patients in an integrated health care system.

American Society of Clinical Oncology-recommended surveillance and physician specialty among long-term breast cancer survivors.

Background: It is unclear whether it is appropriate to transfer the follow-up care of breast cancer (BrCa) survivors from cancer specialists to primary care physicians (PCPs). This contemporary study compared physician specialty and documented the long-term surveillance of survivors who underwent surgery at an American academic center.

Methods: Women in this institutional review board-approved study underwent breast surgery between 1996 and 2006.

Absolute stereochemical determination of chiral carboxylic acids.

Monoamidation of 1,4-diaminobenzene with alpha-chiral carboxylic acids leads to a carrier strategy for absolute stereochemical determination with bis-zinc porphyrin tweezers by exciton-coupled circular dichroism (ECCD). The helicity induced in the porphyrin tweezers upon complexation with the derivatized carrier originates from the preferred conformation of the C(carbonyl)-C(chiral) bond. Correct ECCD signs can be predicted by the rotamer that places the large group perpendicular to the carbonyl group with the small group facing the porphyrin.