Introduction: The current study examined the relationship between subjective memory complaints (both self- and informant-report), objective memory performance, and medial temporal lobe (MTL) volume.
Methods: MCI patients (=58) and their informants (=51) completed the Memory Assessment Clinics Self (MAC-S) and Family (MAC-F) rating scales as a measure of subjective memory. RBANS Immediate and Delayed Memory indices were used as objective measures of memory and a subset of MCI participants also underwent MRI, which was used to measure MTL volume.
Two forms of spatial processing are involved in object location memory. Coordinate processing uses a fine-grained code to provide exact knowledge for the location and is believed dependent on the right posterior parietal cortex (PPC). Categorical processing relies on spatial relationships between objects and is believed dependent on the left PPC.
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