Extending the range of switchable-hydrophilicity solvents.

A switchable-hydrophilicity solvent (SHS) is a solvent that in one state forms a biphasic mixture with water but can be reversibly switched to another state that is miscible with water. All of the amine SHSs that we have reported previously lie within a particular basicity and hydrophilicity range (9.5 < pKaH < 11 and 1.