Heterogeneous knowledge of childhood seizures and epilepsy care in Canadian healthcare Providers: Identifying the gaps.

Epilepsy is the most common chronic neurological condition in children. Many barriers exist in early recognition which cause delay in care and impact quality of life. Some of these children require advanced treatments which are underutilized due to lack of education, awareness and referrals.

The lost generation of Pemphigus populiglobuli (Hemiptera, Aphididae): exploring the taxonomy of the Svalbard aphids of genus Pemphigus.

Species identification within the aphid genus Pemphigus Hartig, 1839 poses challenges due to morphological similarities and host-plant associations. Aphids of this genus generally exhibit complex life cycles involving primary hosts (poplars) and secondary (mostly unrelated herbaceous) host-plants, with some species relying solely on root-feeding generation. An example is a representative of the genus Pemphigus, trophically associated with grass roots, found in the High Arctic Svalbard archipelago.

Analysis of forensic polymer samples using double shot pyrolysis gas chromatography - Mass spectrometry.

Polymers are present in many different products, such as paints, plastics, and rubbers, which are routinely encountered in forensic casework. Comparison of such samples involves an initial visual examination followed by comparison of the chemical compositions of the exhibits. Techniques such as Fourier transform infrared spectroscopy (FTIR) and pyrolysis gas chromatography - mass spectrometry (PyGC-MS) have been reported for determining the chemical compositions of polymers in forensic samples.

Regulation of muscle pyruvate dehydrogenase activity and fuel use during exercise in high-altitude deer mice.

Adult, lab-reared, highland deer mice acclimate to hypoxia by increasing reliance on carbohydrates to fuel exercise. Yet neither the underlying mechanisms for this shift in fuel use nor the impact of lifetime hypoxia exposure experienced in high alpine conditions, are fully understood. Thus, we assessed the use of fuel during exercise in wild highland deer mice running in their native environment.

Network resonance and the auditory steady state response.

The auditory steady state response (ASSR) arises when periodic sounds evoke stable responses in auditory networks that reflect the acoustic characteristics of the stimuli, such as the amplitude of the sound envelope. Larger for some stimulus rates than others, the ASSR in the human electroencephalogram (EEG) is notably maximal for sounds modulated in amplitude at 40 Hz. To investigate the local circuit underpinnings of the large ASSR to 40 Hz amplitude-modulated (AM) sounds, we acquired skull EEG and local field potential (LFP) recordings from primary auditory cortex (A1) in the rat during the presentation of 20, 30, 40, 50, and 80 Hz AM tones.

Strong Prediction: Language Model Surprisal Explains Multiple N400 Effects.

Theoretical accounts of the N400 are divided as to whether the amplitude of the N400 response to a stimulus reflects the extent to which the stimulus was predicted, the extent to which the stimulus is semantically similar to its preceding context, or both. We use state-of-the-art machine learning tools to investigate which of these three accounts is best supported by the evidence. GPT-3, a neural language model trained to compute the conditional probability of any word based on the words that precede it, was used to operationalize contextual predictability.

Migration increases mitochondrial oxidative capacity without increasing reactive oxygen species emission in a songbird.

Birds remodel their flight muscle metabolism prior to migration to meet the physiological demands of migratory flight, including increases in both oxidative capacity and defence against reactive oxygen species. The degree of plasticity mediated by changes in these mitochondrial properties is poorly understood but may be explained by two non-mutually exclusive hypotheses: variation in mitochondrial quantity or in individual mitochondrial function. We tested these hypotheses using yellow-rumped warblers (Setophaga coronata), a Nearctic songbird which biannually migrates 2000-5000 km.

Brain responses to a lab-evolved artificial language with space-time metaphors.

What is the connection between the cultural evolution of a language and the rapid processing response to that language in the brains of individual learners? In an iterated communication study that was conducted previously, participants were asked to communicate temporal concepts such as "tomorrow," "day after," "year," and "past" using vertical movements recorded on a touch screen. Over time, participants developed simple artificial 'languages' that used space metaphorically to communicate in nuanced ways about time. Some conventions appeared rapidly and universally (e.

Ecology, ethology, and evolution in the Anthropocene.

The 53rd Ontario Ecology, Ethology, and Evolution Colloquium (OE3C 2023) took place at Western University (London, Canada) on 25-27 May 2023, attracting 160 participants. This Meeting Review aims not only to recapitulate what was discussed during the event, but also to provide a brief synthesis of how biologists can move forward. The event was organised and run by graduate students and postdoctoral researchers from the Department of Biology at Western University.

Mitochondrial techniques for physiologists.

Mitochondria serve several important roles in maintaining cellular homeostasis, including adenosine triphosphate (ATP) synthesis, apoptotic signalling, and regulation of both reactive oxygen species (ROS) and calcium. Therefore, mitochondrial studies may reveal insights into metabolism at higher levels of physiological organization. The apparent complexity of mitochondrial function may be daunting to researchers new to mitochondrial physiology.

Climate change effects on terrestrial parasitic nematodes: Where are the knowledge gaps?

Climate change is expected to affect parasitic nematodes and hence possibly parasite-host dynamics and may have far-reaching consequences for animal health, livestock production, and ecosystem functioning. However, there has been no recent overview of current knowledge to identify how studies could contribute to a better understanding of terrestrial parasitic nematodes under changing climates. Here we screened almost 1,400 papers to review 57 experimental studies on the effects of temperature and moisture on hatching, development, survival, and behaviour of the free-living stages of terrestrial parasitic nematodes with a direct life cycle in birds and terrestrial mammals.

Geodynamically corrected Pliocene shoreline elevations in Australia consistent with midrange projections of Antarctic ice loss.

The Mid-Pliocene represents the most recent interval in Earth history with climatic conditions similar to those expected in the coming decades. Mid-Pliocene sea level estimates therefore provide important constraints on projections of future ice sheet behavior and sea level change but differ by tens of meters due to local distortion of paleoshorelines caused by mantle dynamics. We combine an Australian sea level marker compilation with geodynamic simulations and probabilistic inversions to quantify and remove these post-Pliocene vertical motions at continental scale.

In focus: perplexing increase of urinary stone disease in children, adolescent and young adult women and its economic impact.

Background: Urinary stone disease (USD) historically has affected older men, but studies suggest recent increases in women, leading to a near identical sex incidence ratio. USD incidence has doubled every 10 years, with disproportionate increases amongst children, adolescent, and young adult (AYA) women. USD stone composition in women is frequently apatite (calcium phosphate), which forms in a higher urine pH, low urinary citrate, and an abundance of urinary uric acid, while men produce more calcium oxalate stones.

Sex differences in perceived speech intelligibility in patients with facial nerve palsy.

Purpose: Facial nerve palsy (FNP) affects physical and social function, including speech. There exists discrepancy between professional and patient perception of appearance following FNP; however, speech differences remain unknown. We aimed to compare ratings of speech intelligibility by different listeners.

Inequality persists in a large citizen science programme despite increased participation through ICT innovations.

Biological recording is a prominent and widely practised form of citizen science, but few studies explore long-term demographic trends in participation and knowledge production. We studied long-term demographic trends of age and gender of participants reporting to a large online citizen science multi-taxon biodiversity platform ( www.artportalen.

Interactions between winter temperatures and duration of exposure may structure Arctic microarthropod communities.

The Arctic has a diverse terrestrial microarthropod fauna which overwinters in situ in soil and vegetation. This fauna is involved in key ecosystem processes, for example decomposition and pollination, and has tolerance to the Arctic's winter conditions. However, the Arctic is undergoing rapid change.

Oral Incompetence: changes in speech intelligibility following facial nerve paralysis.

Background: Speech may be compromised following facial nerve paralysis (FNP), depending on the cause of the paralysis. This can result in lower quality of life and a reduced capacity to return to vocational roles. Despite its prevalence, it is incompletely understood and rarely described.

Implications of past and present genetic connectivity for management of the saltwater crocodile ().

Effective management of protected species requires information on appropriate evolutionary and geographic population boundaries and knowledge of how the physical environment and life-history traits combine to shape the population structure and connectivity. Saltwater crocodiles () are the largest and most widely distributed of living crocodilians, extending from Sri Lanka to Southeast Asia and down to northern Australia. Given the long-distance movement capabilities reported for , management units are hypothesised to be highly connected by migration.

Qualitative analysis of values and motivation reported by families utilizing a paediatric virtual care emergency clinic launched during the SARS-CoV-2 pandemic.

Purpose: This is the first study to take an in-depth qualitative approach to identify motivating factors for caregivers who chose the paediatric emergency virtual care option in Canada during the SARS-CoV-2 pandemic. The role that virtual care may play moving forward is also considered.

Methods: Between May 2020 and May 2021, 773 respondents attending the virtual clinic completed a follow-up survey with open-ended questions.

Sea-level rise in Southwest Greenland as a contributor to Viking abandonment.

The first records of Greenland Vikings date to 985 CE. Archaeological evidence yields insight into how Vikings lived, yet drivers of their disappearance in the 15th century remain enigmatic. Research suggests a combination of environmental and socioeconomic factors, and the climatic shift from the Medieval Warm Period (~900 to 1250 CE) to the Little Ice Age (~1250 to 1900 CE) may have forced them to abandon Greenland.

Outcomes of immediate facial nerve reanimation with nerve transfer for facial nerve neoplasm-induced paralysis: a retrospective review.

Background: The purpose of this study was to evaluate the outcomes of our polyneural, zone-based reanimation approach for patients with neoplasm-induced facial paralysis.

Methods: A retrospective review of consecutive patients who underwent facial reanimation surgery using multiple donor nerve transfers was undertaken. In each case, the selection of donor nerves was based on the availability of donor nerve and the viability of the motor endplate on the affected side.

Function of left ventricle mitochondria in highland deer mice and lowland mice.

To gain insight into the mitochondrial mechanisms of hypoxia tolerance in high-altitude natives, we examined left ventricle mitochondrial function of highland deer mice compared with lowland native deer mice and white-footed mice. Highland and lowland native deer mice (Peromyscus maniculatus) and lowland white-footed mice (P. leucopus) were first-generation born and raised in common lab conditions.

Utility of an oral competence questionnaire for patients with facial nerve paralysis.

Objective: To investigate the utility of a patient-reported outcome measure that evaluates oral competence; speech and swallowing functions after facial nerve paralysis (FNP).

Methods: The Oral Competence Questionnaire (OCQ) covers 16 questions from known, validated patient-reported outcome measures. The OCQ was completed by 40 patients with facial nerve paralysis (FNP) and 40 healthy controls.

Experimentally increased snow depth affects high Arctic microarthropods inconsistently over two consecutive winters.

Climate change induced alterations to winter conditions may affect decomposer organisms controlling the vast carbon stores in northern soils. Soil microarthropods are particularly abundant decomposers in Arctic ecosystems. We studied whether increased snow depth affected microarthropods, and if effects were consistent over two consecutive winters.