Publications by authors named "Cottam D"

During major flood events, waterborne contaminants are relatively poorly characterized. This is due to logistical difficulties associated with obtaining water samples in potentially dangerous flood conditions. Herein, we report analyses of water samples from a large, flooded landscape in Victoria, Australia, during a major flood event.

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Sodium-glucose cotransporters (SGLT) and glucose transporters (GLUT) have been shown to influence diabetes management by modulating glucose uptake by the intestine. Therefore, alterations in gastrointestinal anatomy during bariatric surgery can change SGLT and GLUT receptor activity. These changes offer an additional mechanism for weight loss and may explain the differential impact of the various bariatric surgical procedures.

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Background: Roux-en-Y gastric bypass (RYGB) has consistently demonstrated excellent weight loss and comorbidity resolution. However, outcomes vary based on patient's BMI. Single anastomosis duodeno-ileostomy with sleeve (SADI-S) is a novel procedure with promising short-term results.

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Article Synopsis
  • - A global trend is shifting outpatient procedures, including sleeve gastrectomy (SG), to ambulatory surgical settings, but more research is needed to confirm safety before broad implementation.
  • - This study focuses on collecting data from 365 patients who underwent outpatient laparoscopic sleeve gastrectomy, ensuring it meets the American Society for Metabolic and Bariatric Surgery’s criteria for safety.
  • - Results showed low complication rates (1.6%) and no reported mortalities, indicating that same-day discharge after SG can be safe for carefully selected patients in experienced medical centers.
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Waterborne diseases are known as a leading cause of illness and death in both developing and developed countries. Several pathogens can be present in contaminated water, particularly waters containing faecal material; however, routine monitoring of all pathogens is not currently possible. , which is present in the microflora of human and animals has been used as a faecal indicator in water due to its abundance in surface water and soil.

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The current diagnosis of acute kidney injury relies on the measurement of serum creatinine levels and urine output. However, both measures are subject to considerable limitations; for example, change in serum creatinine levels ideally requires a knowledge of baseline function that is often not available. Furthermore, creatinine levels are influenced by many factors including diet, drug therapy, muscle mass, gender and ethnicity, which may lead to underestimation of the extent of renal dysfunction.

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Background: Thromboprophylaxis in bariatric surgery is widely debated; however, few large articles evaluate treatment plans and their efficacy. Herein, we make the first large-scale report of the safety and efficacy of apixaban (Eliquis) for thrombus prevention following bariatric surgery.

Purpose: To evaluate the safety and efficacy of apixaban following bariatric surgery.

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Background: There is a range of magneto-inertial measurement unit (MIMU) systems commercially available, however sensor specifications and fusion methods vary considerably between manufacturers. Such variability can influence the concurrent validity of MIMUs relative to reference standard measurement devices. Different MIMUs have been compared during static or low-velocity conditions, with higher-velocity movements assessed in robotic-based studies.

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Purpose Of Review: Although initially kidney involvement in COVID-19 infection was felt to occur relatively infrequently, this has proved not to be the case. In critically ill patients with COVID-19, multiorgan failure including acute kidney injury (AKI) is common and is associated with an increased risk of mortality and morbidity. This review focuses briefly on the epidemiology and pathophysiology of COVID-19 associated AKI as well as options for management.

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 Magneto-inertial measurement unit (MIMU) systems allow calculation of simple sensor-to-sensor Euler angles, though this process does not address sensor-to-segment alignment, which is important for deriving meaningful MIMU-based kinematics. Functional sensor-to-segment calibrations have improved concurrent validity for elbow and knee angle measurements but have not yet been comprehensively investigated for trunk or sport-specific movements. This study aimed to determine the influence of MIMU functional calibration on thorax and lumbar joint angles during uni-planar and multi-planar, sport-specific tasks.

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Background: There are no comparative studies on the long-term outcomes after the primary traditional duodenal switch (DS) and single-anastomosis duodeno-ileostomy with sleeve gastrectomy (SADI-S).

Purpose: This study aims to compare the long-term outcomes in a matched cohort.

Setting: This study took place in a single private institute, in the USA.

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Single-anastomosis duodenal ileostomy with sleeve gastrectomy (SADI-S) is an important emerging procedure in bariatric surgery as an alternative to performing the Roux-en-Y gastric bypass (RYGB) or the Roux-en-Y duodenal switch. With this significant weight loss and low weight regain, SADI-S has low complication rates. SADI-S, because of its anatomic configuration, also does not increase ulcer risk in patients, with almost no ulcers observed.

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Purpose: Risk of nutritional disorders (NDs) in bariatric surgical patients has led to guideline recommendations for pre- and post-operative nutrient deficiency screening. The aim of this study was to identify baseline factors associated with incident NDs and, in addition, to explore possible differences in health care spending and use between patients with and without incident NDs following bariatric surgery.

Materials And Methods: Using data linked with a state-wide bariatric surgical registry and a state-wide claims database, subjects who underwent bariatric surgery between July 1, 2013, and December 31, 2015, were identified.

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Background: The long-term effectiveness of Roux-en-Y gastric bypass (RYGB) and single-anastomosis duodeno-ileostomy with sleeve gastrectomy (SADI-S) is unknown.

Purpose: Compare the long-term outcomes.

Setting: Single private institute, USA.

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The Roux-en-Y gastric bypass (RYGB) is the second most common bariatric procedure in the USA. Although the RYGB is an effective procedure, some patients will not achieve optimal weight loss or will experience significant weight regain. In this video report, we present a step-by-step surgical technique of RYGB limb distalization in a 49-year-old female patient for inadequate weight loss.

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Background: The long-term outcomes of primary single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) have never been reported in the literature.

Objectives: The study aimed to evaluate the long-term outcomes after primary laparoscopic SADI-S (LSADI-S).

Setting: Single, private institute, United States.

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This video shows a case of a 57-year-old female patient with morbid obesity who underwent a laparoscopic single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S).

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In April 2020, the US Food and Drug Administration granted emergency use authorization for certain medical devices to be used in patients with coronavirus disease 2019 (CO-VID-19). This included extracorporeal blood purification devices. This narrative review will give a brief overview regarding some of the extracorporeal devices that could be used to treat COVID-19 patients, including the Seraph® 100 Microbind® Affinity Blood Filter, produced by ExThera Medical (Martinez, CA, USA), first licensed in the European Economic Area in 2019.

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Background: Postoperative healthcare cost and use among patients with and without preoperative mental health illness are not well known.

Objective: This study compared total healthcare spending and use (emergency department [ED] visits and inpatient admissions) after 1 year post operation of those with and without preoperative mental health disorders.

Setting: United States.

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Background: Internal hernias have not been reported with primary laparoscopic single anastomosis duodeno-ileostomy with sleeve gastrectomy (LSADI-S). This is the first reported case of an internal hernia following primary LSADI-S and its surgical treatment.

Case Presentation: In this video case report, we present a case of a 54-year-old woman with a BMI of 53 kg/m2 who had undergone a primary LSADI-S for morbid obesity.

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Introduction: Single-anastomosis duodenal switch has been suggested to be an effective bariatric procedure that offers excellent weight loss and by lengthening the common channel the potential to reduce micronutrient deficiencies.

Purpose: To evaluate the weight loss, comorbidity resolution and the 1-year nutritional outcomes of the single-anastomosis duodenal switch (SADS) procedure.

Setting: Multiple US Hospitals.

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