Publications by authors named "Costa J"

This preliminary study examined the effects of playing walking football with and without a goalkeeper (GK) on physiological, physical, technical, and perceptual variables in older men. Twenty participants (67 ± 4.7 years) engaged in two five vs.

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In Brazil, at least four lineages of influenza A virus circulate pig population: 2009 H1N1 flu pandemic (pH1N1), human-seasonal origin H3N2, H1N1 and H1N2 (huH1 lineages) viruses. Studies related to the occurrence of swine influenza A virus (SIAV) in Brazilian herds have been detecting an increase of occurrence of huH1 lineages. This study aimed to construct recombinant vaccines against the huH1N1 virus and test the immunogens in a murine model.

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Candidiasis is an infectious disease caused by some fungi of the genus Candida. In Brazil, the incidence rate is higher than in European countries and the United States, and health problems occur mainly due to the virulence factors of the fungi, which have made treatment with commercial drugs difficult. Considering the context, plants rich in phenolic compounds, such as those of the genus Piper, have been studied due to their antimicrobial properties.

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Objective: To explore the relationship between different patterns of multimorbidity and the use of sleeping medications in women.

Methods: Population-based cross-sectional study with 1,128 women (aged 20-69 years) in Southern Brazil. Data on sleeping medications were obtained from the question "Do you take/use any medication to be able to sleep?" and identified by the Anatomical Therapeutic and Chemical classification.

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Background: This study evaluated the safety and efficacy of BioMime sirolimus-eluting stent (SES) system, with an ultra-low strut thickness (65 µm), in real-world all-comers population with coronary artery stenosis (CAD).

Methods: This was a post-marketing, multicenter, single-arm, observational clinical registry among patients undergoing intervention for CAD. Patients were clinically followed up at 1, 9, 12, and 24 months after the index percutaneous coronary intervention.

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The objective of this randomized clinical trial was to assess whether early intervention with a nonsteroidal anti-inflammatory drug (NSAID) following a disease alert generated by automated milk feeders could reduce diarrhea severity and improve performance in dairy calves. Seventy-one Holstein calves were enrolled on an automated milk feeder (recorded milk intake and drinking speed) at 3 d of age and received up to 15 L/d (150 g/L) of milk replacer until 35 d of age. An alert that was previously validated as diagnostically accurate to identify calves at risk for diarrhea was used using automated milk feeder data (≤60% rolling dividends in milk intake and/or drinking speed over 2 d).

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Edible insects are attracting increasing interest as sustainable alternative protein sources. Despite being considered a safe food for most population, their consumption can pose health risks for allergic patients. This work focused on isolating proteins from the four-European Union approved insects (Tenebrio molitor, Alphitobius diaperinus, Acheta domesticus, and Locusta migratoria) and evaluating their potential immunoglobulin E (IgE)-reactivity with crustacean-allergic patients' sera.

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Background: cashew nut is an almond known for its cardiovascular benefits in adults and weight gain effects in malnourished children, as supported by research. However, its impact on overweight children remains unexplored.

Objective: to analyze the effect of consuming biscuits made with cashew nut flour on the blood glucose and serum triglyceride levels of children with overweight/obesity over four weeks.

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Background: Haptics-enhanced virtual reality (VR-haptic) simulation in dental education has evolved considerably during the past decade, representing a promising resource of simulation-based training opportunities to support conventional practice. We aim to summarize current literature on the applications of VR-haptics in learning, practicing, and teaching dental education.

Methods: A literature search was performed using PubMed, focusing on research articles published between January 2010 and January 2024.

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Roe deer meat is a prized game product in many European countries. However, concerns exist regarding the accuracy of the amount of declared roe deer in processed game meat foods. This study aimed to develop a reliable method for the detection and quantification of roe deer in commercialized game meat products.

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Microglia are crucial for brain development and their function can be impacted by postnatal insults, such as early-life allergies. These are characterized by an upregulation of interleukin (IL)-4 levels. Allergies share a strong comorbidity with Autism Spectrum Disorders (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD).

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Interdevice precision and accuracy are not investigated for precision livestock farming (PLF) technologies, but are fundamental for the use of data in populational metrics and to compare cows' data. This study aimed to validate a behavior monitoring collar (BMC; CowMed, Santa Maria, RS, Brazil) and its interdevice reliability. First, we compared observations with the BMC, and second the interdevice precision and accuracy for rumination, feeding activity, and idle time of lactating dairy cows.

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Paracentral acute middle maculopathy (PAMM) is a form of ischaemic maculopathy involving infarction of the inner nuclear layer secondary to deep retinal capillary plexus ischaemia. Risk factors include retinal vascular disease and systemic vascular risk factors, which can predispose the eye to ischaemia. Recent reports now show associations with pregnancy and also migraine episodes.

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The demand for therapeutic proteins is growing annually. Novel approaches for the production of these molecules on a large scale are necessary, especially in plants. Plant laticifers could help provide an in vivo cell system for protein production expression that can reduce costs of production and downstream processing.

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Article Synopsis
  • The study highlights the urgent need for improved treatments for chronic myeloid leukemia (CML), given the high incidence and mortality rates among men and women.
  • It investigates the potential enhanced effects of combining inecalcitol with existing therapies imatinib and dasatinib on various cancer cell lines.
  • Results showed that while some cell lines were resistant, AR-230 and LAMA-84-s exhibited significant cell-killing effects, suggesting that the effectiveness of combined treatments varies depending on the specific cell type.
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Background: Paracetamol or acetaminophen (APAP), or acetaminophen, is a widely used medication for pain relief and fever reduction due to its analgesic and antipyretic properties. However, excessive APAP consumption can lead to severe hepatotoxicity and nephrotoxicity, posing overdose risks. Consequently, the development of analytical methods for an accurate and rapid detection of APAP in biological matrices is of great interest in the health-related fields.

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The objective was to analyze the longitudinal associations of physical activity (PA) and Sedentary behavior (SB) on bone health indicators (BHI) in healthy young adults. Articles were selected from five databases and 17 longitudinal studies were selected after meeting the inclusion and exclusion criteria. Among these, only one study assessed the association between childhood PA and adult BHI, the results showed no significant association between PA and BHI.

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Introduction: Determining the bittering profile of hops is a prerequisite for their use in beer making industry. To fully grasp the brewing potential of Corsican hops, it is therefore essential to perform a precise quantification of the molecules responsible for their bittering power.

Objective: The aim of this study is highlighting of the bittering profile of Corsican hops.

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Article Synopsis
  • Apigenin, a flavonoid thought to benefit cardiovascular health, was studied for its effects on vascular function in Spontaneously Hypertensive Rats (SHRs) to understand its mechanisms of action.
  • Vascular beds from SHRs were tested with varying doses of apigenin, showing that its ability to lower blood pressure depended on the presence of endothelial cells and was significantly reduced by inhibitors of nitric oxide and potassium channels.
  • The research concluded that apigenin causes vasodilation primarily through endothelial nitric oxide and calcium-activated potassium channels, suggesting its potential for therapeutic use in cardiovascular diseases and the need for more clinical studies.
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Background/objectives: Trypanosomiasis and bovine babesiosis correspond to important diseases that cause great economic losses, but there are still no studies evaluating their occurrence in herds of dairy cattle in Ceará. The aim of this study was to perform molecular diagnosis of the main hemoparasites of dairy cows in the microregion of the central hinterland of Ceará.

Methods: For the molecular diagnosis of parasites, genomic material was extracted and polymerase chain reaction directed to the cdCatL-like gene for and SS rRNA of and was performed.

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A 44-year-old female with an established diagnosis of autosomal dominant polycystic kidney disease (based on imaging findings and family history) was being evaluated for weight loss, early satiety and progressive abdominal distension. Kidney function had been relatively stable for years. Because of a history of multiple liver cysts on ultrasonography, the patient was referred for Gastroenterology for evaluation.

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Article Synopsis
  • Biosensors targeting food allergens, like Gly m TI in soybeans, enhance individual health safety and public health by facilitating compliance with food regulations and reducing allergen-related recalls.
  • Recent developments in biosensor technology, like portability and real-time monitoring, broaden their applications in food production, food service, and even home environments, making them essential tools for allergen detection.
  • A novel Gly m TI-MIP biosensor was successfully created to identify soybean protein in a variety of complex food matrices, achieving high sensitivity and minimizing cross-reactivity, thus improving food safety protocols for both processed and unprocessed foods.
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Objectives: To investigate the causes of failure in unicompartmental knee arthroplasty (UKA), types of implants used in the revision, evaluate the need to use tibial stems, metal block augmentations, and bone grafts during conversion to total knee arthroplasty (TKA).

Methods: In a 10-year retrospective analysis, focussing on cases of UKA failure, our study aimed to categorise early and late failures, determine the primary failure modes and assess the utilisation of bone augmentations and grafts during conversion to TKA. We evaluated patient data, diagnoses, procedure intervals, and follow-up periods to provide a comprehensive understanding of the conversion process.

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To fight counterfeits and to protect the consumer, the interest in certifying the origin of agricultural goods has been steadily growing in the last years. While numerous works focus on the finished product, an aspect often overlooked is the origin of the raw materials and the direct correlation between chemicals in the soil and the plants. With inductively coupled plasma mass spectrometry (ICP-MS) analysis, trace and ultratrace elements in Sangiovese grapes (the main component of Chianti wine) were measured and their levels were used to investigate the geographical origin of the samples.

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Anxiety and depression are mental disorders that have been exponentially increasing over the last decades. Psychopharmacology emerged to try to alleviate the symptoms of these disorders; however, the side effects and the time it takes to achieve the desired effect are factors that decrease the search for and adherence to treatment. To remedy this situation, new compounds capable of improving the performance of these medications and reducing their adverse effects have been sought.

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