Publications by authors named "Cosmina Mija"

Article Synopsis
  • From August to November 2023, Italy reported 82 local cases of Dengue virus (DENV), with 10 cases specifically studied in Rome, showcasing a shift toward local transmission of the disease.
  • The affected patients, mostly middle-aged and presenting classic dengue symptoms, were confirmed to have the virus through various laboratory tests including detection of DENV proteins and antibodies.
  • The study emphasizes the importance of developing better surveillance and diagnosis strategies for DENV infections in non-endemic regions, to manage and understand the clinical progression of the disease.
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Article Synopsis
  • The study focused on the effectiveness of tixagevimab/cilgavimab (T/C) as pre-exposure prophylaxis (PrEP) in immunocompromised individuals, categorizing them into groups based on their COVID-19 history.
  • A total of 231 participants were included, with a significant portion having hematological diseases and receiving multiple vaccine doses; breakthrough infections (BTIs) occurred in 56 participants (24%) but were mostly mild to moderate.
  • Immune markers were measured over time, showing an initial increase in anti-RBD IgG antibodies at 3 months, a decline at 6 months, and low neutralizing antibodies, reinforcing T/C's clinical efficacy in reducing severe COVID-19
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SARS-CoV-2 is a highly infectious virus responsible for the COVID-19 pandemic. Therefore, it is important to assess the risk of SARS-CoV-2 infection, especially in persistently positive patients. Rapid discrimination between infectious and non-infectious viruses aids in determining whether prevention, control, and treatment measures are necessary.

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Since August 2023, outbreaks of dengue virus (DENV) infection have occurred in Italy. We report 2 autochthonous case-patients and their extended follow-up. Despite persistent DENV detected in blood by PCR, results for antigenomic DENV RNA were negative after day 5, suggesting that a 5-day isolation period is adequate to avoid secondary cases.

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