Publications by authors named "Cosmina B Zeana"

Article Synopsis
  • A study focused on 13 patients with advanced HIV (CD4 count under 200 cells/μL) who also had severe mpox and multiple organ issues.* -
  • These patients underwent long treatments with various medications, including tecovirimat and others, but still faced serious health complications.* -
  • The outcomes showed that they had long hospital stays and a high death rate, highlighting the severity of their conditions.*
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We report a case of bacteremia and septic thrombophlebitis of the ovarian vein as a rare puerperal complication in a young patient. She was successfully managed with subcutaneous low molecular weight heparin (LMWH) and intravenous (IV) antibiotics before transitioning to a prolonged course of oral antibiotics at discharge.

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We report a case of progressive, severe mpox virus (MPXV) infection in a patient with AIDS despite a standard course of tecovirimat. He significantly improved after administration of vaccinia immune globulin intravenous (VIGIV) highlighting its use as an adjunct for severe disease in immunocompromised hosts.

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Article Synopsis
  • Carbapenems are crucial for treating severe infections from resistant gram-negative bacteria, but a new challenge has emerged with the discovery of KPC-type carbapenemases, which complicate treatment options.
  • In a Manhattan hospital, seven patients with bloodstream infections from carbapenem-resistant Klebsiella pneumoniae were studied, revealing that all isolates belonged to a single clone and carried the (bla)KPC gene for resistance.
  • Out of six patients with these infections, only two survived, demonstrating the high mortality associated with KPC-2 carbapenemase-producing organisms and emphasizing the need for effective treatment strategies.
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