Publications by authors named "Cosmas Samuel"
Article Synopsis
- LLPS (Liquid-liquid phase separation) is a reversible process where a homogeneous fluid separates into two distinct liquid phases: a dilute phase and a condensed phase.
- Recent studies highlight LLPS as a key principle for intracellular organization, contributing to the formation of membraneless organelles (MLOs) like P bodies, nucleolus, and stress granules.
- LLPS is also linked to the regulation of various biological processes, including signal transduction, chromatin rearrangement, and RNA metabolism.
Background: The 2019-nCoV which is regarded as a novel coronavirus is a positive-sense single-stranded RNA virus. It is infectious to humans and is the cause of the ongoing coronavirus outbreak which has elicited an emergency in public health and a call for immediate international concern has been linked to it. The coronavirus main proteinase which is also known as the 3C-like protease (3CLpro) is a very important protein in all coronaviruses for the role it plays in the replication of the virus and the proteolytic processing of the viral polyproteins.
View Article and Find Full Text PDFThe effect of aqueous extract of Acacia albida stem bark was investigated in Wistar albino rats infected with Trypanosoma evansi. The extract showed highest reduction in parasitemia at the dose of 600 mg/kg body weight (bw). A dose of 300 mg/kg bw improved packed cell volume the most by 14.
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