Can ChatGPT generate surgical multiple-choice questions comparable to those written by a surgeon?

Background: This study aimed to determine whether surgical multiple-choice questions generated by ChatGPT are comparable to those written by human experts (surgeons).

Methods: The study was conducted at a medical school and involved 112 fourth-year medical students. Based on five learning objectives in general surgery (colorectal, gastric, trauma, breast, thyroid), ChatGPT and surgeons generated five multiple-choice questions.

Ethical Approaches in General Surgery Residency Training: A Blended Learning Module Trial.

Aim: This study aimed to develop a blended training module focusing on ethical approaches within general surgery residency training and to assess the impact of this training on participants.

Methods: Based on the literature review and input from both general surgery residents and trainers, 14 topics were identified, and corresponding learning objectives were formulated. The training was conducted through a blended learning module, which encompassed online video presentations alongside face-to-face sessions involving real-life cases.

Wilson Disease and the COVID-19 pandemic: exploring patients' mental health and vaccination attitudes in a longitudinal study.

Introduction: The COVID-19 pandemic significantly impacted the mental health of individuals with chronic conditions such as Wilson's Disease (WD). This study investigates stress, anxiety, depression, quality of life, cognitive function, vaccination rates, infection rates, and perceptions related to the pandemic and vaccines among WD patients.

Methods: The study analyzed COVID-19 perceptions and vaccine attitudes of 62 adult WD patients enrolled in the international multisite WD Registry.

Taste and smell function in Wilson's disease.

Objective: Wilson's disease (WD) is a metabolic disorder associated with abnormal copper metabolism that results in hepatic, psychiatric, and neurologic symptoms. No investigation of taste function has been made in patients with WD, although olfactory dysfunction has been evaluated.

Methods: Quantitative taste and smell test scores of 29 WD patients were compared to those of 790 healthy controls.

Major Depressive Disorder in an International Multisite Wilson Disease Registry.

Background And Aims: Psychiatric symptoms are frequently reported in Wilson disease (WD); however, systematic assessments with validated measures are lacking.

Objective: We aim to report the prevalence and clinical correlates for major depressive disorder (MDD) as resulting from a multisite international WD registry.

Methods: All patients enrolled in the WD registry received structured psychiatric evaluations (Mini International Neuropsychiatric Interview, Patient Health Questionnaire-9, Generalized Anxiety Disorder-7 scale, Perceived Stress Scale), laboratory tests, hepatology, and neurological assessments.

Neural network-based cooling design for high-performance processors.

Ultra-high chip power densities that are expected to surpass 1-2kW/cm in future high-performance systems cannot be easily handled by conventional cooling methods. Various emerging cooling methods, such as liquid cooling via microchannels, thermoelectric coolers (TECs), two-phase vapor chambers, and hybrid cooling options have been designed to efficiently remove heat from high-performance processors. However, selecting the optimal cooling solution for a given chip and determining the optimal cooling parameters for that solution to achieve high efficiency are open problems.

HPC Data Center Participation in Demand Response: an Adaptive Policy with QoS Assurance.

Demand response programs help stabilize the electricity grid by providing monetary stimulus to consumers if they regulate their power consumption following market requirements. Regulation service, a market that requires participants to regulate power by following a signal updated every few seconds, is particularly beneficial to HPC data centers since data centers are capable of increasing/decreasing power consumption owing to the flexibility in running workloads and the availability of power control mechanisms. While prior works have explored how data centers can provide regulation service reserves, Quality-of-Service (QoS) provisioning for the jobs running at the data centers has not been considered.

The Effect of Mental Health, Neurological Disease, and Liver Disease on Quality of Life in Patients With Wilson Disease.

Background: Wilson disease (WD) is a chronic disorder of copper metabolism which may affect patient's quality of life (QOL).

Objective: Our aim was to assess the relationship between mental QOL (M-QOL) and physical QOL (P-QOL) and severity of the liver, neurological disease and mental health in patients with WD.

Methods: At enrollment into our multisite international WD registry, adults (n = 62) were administered examinations assessing QOL (Short-Form 12-Item Health Survey), cognition, and mood.

Direct Measurement of ATP7B Peptides Is Highly Effective in the Diagnosis of Wilson Disease.

Background & Aims: Both existing clinical criteria and genetic testing have significant limitations for the diagnosis of Wilson disease (WD), often creating ambiguities in patient identification and leading to delayed diagnosis and ineffective management. ATP7B protein concentration, indicated by direct measurement of surrogate peptides from patient dried blood spot samples, could provide primary evidence of WD. ATP7B concentrations were measured in patient samples from diverse backgrounds, diagnostic potential is determined, and results are compared with biochemical and genetic results from individual patients.

The rise of the Red Crescent.

This paper addresses the establishment of the Red Crescent, an equivalent of the Red Cross, in the Ottoman Empire in 1868 through the founding of 'the Society of Care and Aid for Wounded and Disabled Soldiers' (Mecrȗhȋnve Marzȃ-yi Askeriyeye İmdad ve Muavenet Cemiyeti). Following initial slow development, the Society was revitalized in April 1877 in preparation for war with Russia. Importantly, the 1877-1878 Ottoman-Russian conflict was the first major war conducted by signatories of the 1864 First Geneva Convention, which made provisions for the treatment of wounded and sick soldiers and protection for those providing care.

The Effectiveness and Feasibility of Laparoscopic Re-sleeve Gastrectomy.

Background: Weight regain following laparoscopic sleeve gastrectomy (LSG) may be due to dilation of the gastric reservoir. Laparoscopic re-sleeve gastrectomy (LrSG) is among the revisional surgery options.

Objectives: We aimed to investigate the effectiveness of LrSG for weight loss after a 12- and 24-month follow-up period.

Comparison of Weight Loss in Sleeve Gastrectomy Patients With and Without Antrectomy: a Prospective Randomized Study.

Background: Laparoscopic sleeve gastrectomy (LSG) restricts gastric volume to achieve weight loss. We aimed to compare the efficacy of LSG with and without antrectomy for achieving weight loss.

Methods: The prospective randomized study comprised 127 obese patients that underwent either LSG with antrectomy (2 cm to pylorus) (group 1) or LSG without antrectomy (6 cm to pylorus) (group 2), using 36 Fr and 32 Fr bougies, respectively.

Transcriptional down-regulation of in a subset of HIV+ controllers and their family members.

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of . R5 resistance was not observed in macrophages and depended upon the method of T cell activation.