Publications by authors named "Cory Heck"
Background: Proton pump inhibitors (PPIs) and histamine type 2-receptor blockers (H2Bs) are commonly used for stress ulcer prophylaxis among patients requiring invasive mechanical ventilation (IMV). Recent studies suggest an increased mortality associated with PPIs compared to H2Bs, but these studies poorly represent patients with cardiovascular disease or acute myocardial infarction (AMI).
Objectives: The aim of this study was to compare outcomes related to stress ulcer prophylaxis with PPIs compared to H2Bs in patients with AMI requiring IMV.
Objective: Patients with acute myocardial infarction (AMI) complicated by respiratory failure require antiplatelet regimens which often cannot be stopped and may increase bleeding from tracheostomy. However, there is limited available data on both the proportion of patients undergoing tracheostomy and the impact on antiplatelet regimens on outcomes.
Methods: Utilizing the Vizient® Clinical Data Base, we identified patients ≥18 years admitted from 2015 to 2019 with a primary diagnosis of AMI and requiring invasive mechanical ventilation (IMV).
Article Synopsis
- Patients with acute myocardial infarction (AMI) who require invasive mechanical ventilation (IMV) show high mortality rates, and the study focuses on how different induction agents affect their outcomes.
- This research analyzed data from 5,147 AMI patients receiving IMV between 2015 and 2019, comparing outcomes between those induced with propofol and etomidate.
- Results indicated that propofol use resulted in lower mortality than etomidate (32.3% vs 36.1%), suggesting the need for further randomized trials to identify the best induction agent for these critically ill patients.