Publications by authors named "Corte L"
Article Synopsis
- - A rare case of right interstitial pregnancy occurred in a 32-year-old woman who had previously undergone a salpingo-oophorectomy, leading to an emergency room visit due to suspected ectopic pregnancy.
- - After various diagnostic procedures, including ultrasound and hysteroscopy, the patient underwent a successful robot-assisted laparoscopic surgery to remove the interstitial pregnancy while preserving her fertility.
- - The exact cause of this rare pregnancy is unclear, but it may involve fertilization in the intact tube and possible changes in the remaining tubal tissue that allowed the oocyte to implant.
Article Synopsis
- This study investigates the link between inflammation markers (NLR, MLR, PLR) and deep myometrial infiltration in patients with endometrial cancer.
- Conducted at AOU Vanvitelli in Naples, Italy, the research involved 161 patients, examining pre-surgery blood counts and relevant histopathological data using statistical analysis software.
- The findings reveal that while both NLR and MLR are associated with deep myometrial infiltration, only NLR remained significant after accounting for other risk factors like grading and histotype.
Objective: This study aimed to evaluate the efficacy of a new biomarker, termed SIR-En, in identifying patients at risk of endometrial carcinoma among those presenting with abnormal uterine bleeding during menopause.
Material And Methods: A retrospective case-control analysis was conducted on 242 women with menopausal abnormal uterine bleeding and endometrial thickness ≥ 4 mm. Peripheral blood samples were collected within 7 days before histological diagnosis.
Article Synopsis
- The study investigates how adenomyosis may affect surgical outcomes for dyspareunia in patients with rectovaginal endometriosis, identifying significant challenges in treating this condition despite surgery.
- Conducted from January 2020 to July 2023, it analyzed medical records of 94 patients who underwent surgery, comparing those with adenomyosis to those without, assessing pain levels and sexual quality of life before and after the procedure.
- Results indicated that while pain significantly decreased and sexual quality of life improved in both groups, patients without adenomyosis exhibited greater improvements post-surgery.
Women with endometriosis were deemed more prone to COVID-19 infection in some reports. Considering that endometriosis-related aberrant immune response, understanding how COVID-19 vaccination influences its clinical status is crucial. The aim of this meta-analysis was the evaluate the susceptibility to COVID-19 infection and modifications of symptoms following COVID-19 vaccination in women with endometriosis.
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- The study investigates the effectiveness of ultra-low-impact laparoscopy, which combines miniaturized instruments and regional anesthesia, for treating benign gynecological diseases.
- Conducted with 26 women, the study found minimal postoperative pain, quicker recovery times, and a low rate of nausea and vomiting, confirming the method's safety and efficacy.
- The positive outcomes suggest this technique could become a standard in gynecological surgery, warranting further research with more participants to validate its success.
Background: Hereditary breast and ovarian cancer syndrome (HBOC) predisposes women to an increased risk mainly of breast and tubo-ovarian cancer. The aim of the study is to investigate whether being diagnosed with HBOC syndrome is itself a risk factor for sexual dysfunction.
Methods: An ad hoc questionnaire, including baseline demographic and clinical data, and the Sexual Function Questionnaire 28 (SFQ28) were administered to HBOC female carriers (study group) and to a control group.
The occurrence of non-albicans species within the genus poses a major challenge in the clinical setting. , formerly known as , has gained attention due to its potential multidrug resistance, particularly to amphotericin B (AmB). While intrinsic resistance to AmB is rare, secondary resistance may develop during treatment due to phenotypic rearrangement and the reorganization of the cell wall.
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- * The goal is to locate all potential lesion sites, even those not seen by the naked eye, and to evaluate the spread of the disease effectively.
- * This technique was first applied to a 68-year-old patient with a single invasive vulvar Paget's lesion to ensure thorough treatment while minimizing the risk of recurrence and unnecessary damage.
Impact of surgery on reproductive outcomes in women with deep endometriosis and proven presurgical infertility: Facts and controversies.
Best Pract Res Clin Obstet Gynaecol
September 2024
Article Synopsis
- The management of infertility in women with deep endometriosis (DE) is contentious, with insufficient evidence regarding the link between infertility and the severity of DE as categorized by the rASRM stages.* -
- A systematic review encompassing 16 studies found that out of 947 infertile women who underwent surgery, 486 achieved pregnancy, indicating an average pregnancy rate of 51.3% and suggesting surgery may enhance reproductive outcomes, especially when coupled with assisted reproductive technology (ART).* -
- However, due to the varied data and lack of clarity on surgical outcomes relative to the location of DE, stronger conclusions cannot be drawn, highlighting the need for further research to optimize surgical strategies in relation to ART treatments.*
Solid particles placed at the interface between hydrogels and biological tissues can create an adhesive joint through the adsorption of macromolecules onto their surfaces. Here, we investigated how this adhesion by particle bridging depends on the wetting of tissue surfaces and on the heterogeneities in tissue composition. peeling experiments were performed using poly(ethylene glycol) films coated with aggregates of silica nanoparticles deposited on the internal tissues of porcine liver.
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- - Vulvar carcinoma, especially vulvar squamous cell carcinoma (VSCC), is a rare type of cancer that makes up 4% of gynecological tumors; diagnosis typically involves biopsy during vulvoscopy along with imaging techniques like MRI, USG, and PET.
- - A study conducted with data from multiple databases analyzed the effectiveness of imaging for diagnosing and staging VSCC, revealing high sensitivity but lower specificity in identifying malignant lesions, particularly with a mean SUV value of 8.4 in PET scans for tumors.
- - MRI was effective for evaluating lymph node involvement, showing significant accuracy rates, while USG measurements (cortical thickness and short axis length) proved crucial for distinguishing between cancerous and non-cancer
Article Synopsis
- Uterine myomas are a common issue for women of reproductive age, leading to the need for effective treatment options, including robotic-assisted laparoscopic myomectomy (RALM) and traditional laparoscopic myomectomy (LM).
- A study comparing 50 patients (25 RALM, 25 LM) found that RALM had significantly shorter operative times and reduced hospital stays, with an average of 1.2 days compared to 2.9 days for LM.
- However, there were no significant differences in blood loss or hemoglobin levels between the two methods, indicating that while RALM may offer efficiency, both methods are comparable in terms of safety outcomes.
The evolution of regulatory perspectives regarding the health and nutritional properties of industrial hemp-based products ( L.) has pushed research to focus on the development of new methods for both the extraction and formulation of the bioactive compounds present in hemp extracts. While the psychoactive and medicinal properties of hemp-derived cannabinoid extracts are well known, much less has been investigated on the functional and antimicrobial properties of hemp extracts.
View Article and Find Full Text PDFThe role of liquid biopsy in epithelial ovarian cancer: State of the art.
Crit Rev Oncol Hematol
February 2024
Article Synopsis
- * Currently, cfDNA is only approved for targeted treatments in colorectal cancer, non-small cell lung cancer, and breast cancer.
- * Emerging blood-based biomarkers like circulating tumor cells, miRNA, and extracellular vesicles have potential benefits for early diagnosis, prognosis, and treatment response in ovarian cancer patients.
Outcomes of conventional and advanced energy devices in laparoscopic surgery: a systematic review.
Minim Invasive Ther Allied Technol
February 2024
Introduction: Hemostasis is an important step in all surgical procedures. Mechanical methods of hemostasis have been gradually abandoned in favor of electrosurgery. The aim of this systematic review was to evaluate the effectiveness of electrosurgical instruments utilized in minimally invasive gynecological procedures.
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- This study explores the feasibility and outcomes of performing laparoscopic surgery for ectopic pregnancy under spinal anesthesia (SA) compared to general anesthesia (GA).
- A total of 82 women were analyzed, revealing that those under SA experienced less pain immediately after surgery and a quicker recovery, including faster bowel movements and shorter hospital stays.
- Patient satisfaction was higher in the SA group, with 94.3% expressing satisfaction, while general surgeons also reported high satisfaction rates with the procedure.
Article Synopsis
- The study investigates the use of hyperthermic intraperitoneal chemotherapy (HIPEC) following cytoreductive surgery in ovarian cancer patients, focusing on its effectiveness in primary debulking surgery (PDS), interval debulking surgery (IDS), and recurrent ovarian cancer (ROC).
- A systematic review of 14 studies, including randomized controlled trials (RCTs) from 2003 to 2023, revealed no significant difference in survival rates for HIPEC compared to other treatments in PDS, while showing some survival advantages in the HIPEC plus IDS group after neoadjuvant chemotherapy (NACT).
- However, results for ROC patients did not demonstrate significant improvements in progression-free survival (PFS) or overall
Article Synopsis
- Cervical cancer is the fourth most common cancer for women globally, prompting a study on its prevention, early diagnosis, and treatment options, particularly focusing on the role of surgery.
- The study highlights the controversy around using minimally invasive surgery for small tumors and examines the option of fertility-sparing surgery for young women.
- Findings suggest that sentinel node biopsy is preferable for certain tumor sizes and that vaccination and early detection of pre-cancerous lesions are critical for effective cervical cancer prevention.
Article Synopsis
- * This study compared two surgical approaches for fibroid extraction— the ExCITE technique (Group A) and a minilaparotomy procedure (Group B)—analyzing outcomes such as postoperative pain, hospital stay duration, and patient satisfaction.
- * Results showed that Group A experienced significantly less pain within 6 and 12 hours post-surgery, higher patient satisfaction (100% vs 67%), and shorter hospital stays compared to Group B, indicating the ExCITE technique as a favorable minimally invasive
: Meigs syndrome is represented by a benign adnexal tumor, ascites, and hydrothorax. Even though the ovarian mass is often characterized by a fibroma-like origin, cancer antigen-125 (CA-125) serum levels could be elevated as in the development of ovarian cancer. Here, we present the case of a patient with Meigs syndrome and increased CA-125.
View Article and Find Full Text PDFPurpose: To evaluate the agreement rate between hysteroscopy and pathological examination in case of chronic endometritis.
Methods: A retrospective observational study carried out at Gynecology and Obstetrics Department, Puerta de Hierro Hospital, Autónoma University of Madrid, Spain, from January 2021 to June 2022 was performed by obtaining data from 115 medical records of women who underwent office hysteroscopies that was compared with the findings of final histological examination of endometrial biopsy. Cohen's kappa index was used to evaluate this agreement rate.