Lateral neck recurrence from papillary thyroid carcinoma: Predictive factors and prognostic significance.

Objectives/hypothesis: The aim of this study was to identify any possible predictive factors of lateral neck recurrence in patients with papillary thyroid carcinoma with no ultrasonographic and/or cytological evidence of lymph node metastasis at time of diagnosis. The influence of lateral neck recurrence on survival was also investigated.

Study Design: Observational retrospective study.

Necrotizing fasciitis of the neck: considerations about two cases.

Background And Aim Of The Work: Necrotizing fasciitis is a rapidly progressing life-threatening infection of the deep fat and fascial layers, which rarely occurs in the neck. The aim of the paper is to report the management of this rare condition, pointing out the role of multimodality in achieving the cure of the patient.

Methods: We report our experience regarding the management of two cases of necrotizing fasciitis of the neck successfully treated with surgical and medical treatment.

Complications of central neck dissection in patients with papillary thyroid carcinoma: results of a study on 1087 patients and review of the literature.

Background: Prophylactic central neck dissection (CND) has been proposed in the treatment of patients affected by papillary thyroid carcinoma (PTC) with clinically negative neck lymph nodes. The procedure allows pathologic staging of lymph nodes of the central compartment and treatment of the micrometastases. Nevertheless, the morbidity that its routine use adds to the total thyroidectomy must be taken into account.

CT cross-sectional imaging classification system for substernal goiter based on risk factors for an extracervical surgical approach.

Background: The purpose of this study was to identify risk factors for surgical extracervical approach in patients with substernal goiter. We used a novel classification system based on CT scan cross-sectional imaging (CSI) reconstruction.

Methods: Medical records of 4297 patients with thyroid disease operated on at our department were reviewed.

Prognostic factors affecting neck lymph node recurrence and distant metastasis in papillary microcarcinoma of the thyroid: results of a study in 445 patients.

Background: The management of thyroid papillary microcarcinoma (PMC) is controversial. Total thyroidectomy, thyroid lobectomy/isthmectomy, and even no treatment have been proposed. We investigated the clinical course and prognostic factors for disease recurrence and distant metastasis in 445 patients with PMC.

Dedifferentiated acinic cell carcinoma of the parotid gland with myoepithelial features.

Dedifferentiated acinic cell carcinoma of the salivary gland is an uncommon variant of acinic cell carcinoma, characterized by the coexistence of both an usual low-grade acinic cell carcinoma and a high-grade dedifferentiated component, as well as by an accelerated clinical course. We describe a case of acinic cell carcinoma of the parotid gland in a 67-year-old woman, which recurred 4 times after surgery and radiotherapy. The recurrences consisted of residual foci of acinic cell carcinoma intermingled with a high-grade epithelial proliferation; the latter was focally constituted by cells with morphologic and immunohistochemical features of myoepithelium.