Evaluation of treatment outcome using the Patient Specific Functional Scale in knee osteoarthritis patients undergoing multidisciplinary rehabilitation.

Objective: First, to make an inventory of activity limitations commonly reported by knee osteoarthritis (OA) patients undergoing multidisciplinary rehabilitation. Second, to evaluate treatment outcome using the Patient Specific Functional Scale (PSFS) and compare it to the Western Ontario and McMasters Universities Osteoarthritis Index physical function subscale (WOMAC-pf).

Design: An observational study with assessments before and immediately after multidisciplinary rehabilitation.

Dynamics of mallard (Anas platyrynchos) gastrocnemius function during swimming versus terrestrial locomotion.

This study investigates how the contractile function of a muscle may be modulated to accommodate changes in locomotor mode and differences in the physical environment. In vivo recordings of lateral gastrocnemius (LG) activation, force development (measured using tendon buckle transducers) and length change (measured using sonomicrometry) were obtained from mallard ducks (Anas platyrhynchos) as they swam at steady speeds in a water tank and walked or ran on land. LG force recordings were compared with combined lateral and medial gastrocnemius (MG) muscle-tendon force recordings obtained from the contralateral limb, allowing force development by the MG to be estimated relative to that of the LG.

In vivo pectoralis muscle force-length behavior during level flight in pigeons (Columba livia).

For the first time, we report in vivo measurements of pectoralis muscle length change obtained using sonomicrometry combined with measurements of its force development via deltopectoral crest strain recordings of a bird in free flight. These measurements allow us to characterize the contractile behavior and mechanical power output of the pectoralis under dynamic conditions of slow level flight in pigeons Columba livia. Our recordings confirm that the pigeon pectoralis generates in vivo work loops that begin with the rapid development of force as the muscle is being stretched or remains nearly isometric near the end of the upstroke.

In vivo strains in pigeon flight feather shafts: implications for structural design.

To evaluate the safety factor for flight feather shafts, in vivo strains were recorded during free flight from the dorsal surface of a variety of flight feathers of captive pigeons (Columba livia) using metal foil strain gauges. Strains recorded while the birds flew at a slow speed (approximately 5-6 m s-1) were used to calculate functional stresses on the basis of published values for the elastic modulus of feather keratin. These stresses were then compared with measurements of the failure stress obtained from four-point bending tests of whole sections of the rachis at a similar location.

Aberrant interhemispheric alpha coherence on electroencephalography in schizophrenic patients during activation tasks.

Thirty schizophrenic patients (20 medicated, 10 off medication) were compared with 30 normal controls subjects matched for age, sex, handedness and intelligence. During the performance of a frontal activation task, normal subjects showed increased interhemispheric coherence between anterior brain regions. Schizophrenic patients did not show the same amount of bilateral anterior activation.

The relationship of cortical activation to alternating autonomic activity.

It has been proposed that it is possible to selectively activate the cerebral hemispheres, thereby enhancing lateralized cognitive abilities. A proposed method of achieving selective activation is by altering nasal congestion/decongestion (nasal cycle), which is believed to effect a contralateral change in hemispheric activation through the autonomic nervous system (ANS). This hypothesis was tested in 4 right-handed male and 6 right-handed female undergraduate students.

Frontal and non-frontal lobe neuropsychological test performance and clinical symptomatology in schizophrenia.

Schizophrenic subjects performed significantly worse on neuropsychological tests of frontal lobe function but not on tests of non-frontal lobe function when compared to a matched group of normal subjects. Correlations expected between frontal lobe neuropsychological test performance and negative symptoms were not found.

Coherence on electroencephalography and aberrant functional organisation of the brain in schizophrenic patients during activation tasks.

Thirty schizophrenic patients (20 medicated, 10 off medication) were compared with 30 normal control subjects matched for age, sex, handedness, and intelligence. During the performance of left-hemisphere cognitive activation tasks, normal subjects had significantly increased EEG alpha coherence in areas related to left focal frontal sites, with decreases in temporal and posterior areas. Schizophrenic patients did not show the same degree of focal activation of left frontal areas.

EEG "maturational lag" profiles: follow-up analyses.

Nineteen children who had EEG diffuse slow frequency profiles suggesting a maturational lag were retested 1 to 2 years later receiving both EEG and psychometric assessments. They were compared to 18 children who also had been tested previously but did not have the slow frequency profile. Children with the maturational lag profile displayed varying degrees of EEG developmental change upon retest; i.

EEG slow frequency and WISC-R correlates.

On the basis of slow frequency indices obtained from computerized EEG assessments, 36 children were ranked the highest and 23 the lowest in a heterogeneous population of children involved in a brain-behavior assessment program. WISC-R results show the high or excess slow frequency group to have low verbal and normal performance subtest scores, while those with the least slow frequency activity were above normal on verbal and performance scores. Discriminant function analyses of the WISC-R profiles significantly separated the two EEG groupings, with the Information Subtest and Verbal IQ the best discriminating measures.

Taximetric strategies applied to psychiatric classification.

This article discusses limitations inherent in using unilevel behavioral descriptors as the basis for the construction of psychiatric classifications. As an alternative we consider the advantages of the polythetic classification strategy as suggested by Sokal and Sneath (1963) in their description of a "numerical taxonomic" approach. They argue for the development of naturally occurring, empirically defined classes rather than categories based on single domains of behaviors such as psychiatric symptoms.

Telson reflex habituation in Limulus polyphemus.

Muscle correlates of reflex telson movement were recorded in intact Limulus (horseshoe crab) preparations with chronically implanted microelectrodes. Muscle activity habituated during repetitive tactile stimulation of the gills with puffs of air. Dishabituation was also observed, as were inverse relationships between the frequency and intensity of stimulation and the rate of response decrement.

ARTHROPOD PREPARATION FOR BEHAVIORAL, ELECTROPHYSIOLOGICAL, AND BIOCHEMICAL STUDIES.

Electrodes and cannulea can be permanently implanted in the horseshoe crab, Limulus polyphemus. Recordings of electrical activity can be obtained from the optic nerve, heart, and abdominal ganglia and the cannulae are effective routes for introducing isotopes into the nervous system. The animals survive for at least 13 days and are not behaviorally impaired.

Effect of ribonuclease on retention of conditioned response in regenerated planarians.

Conditioned planarians were transected and allowed to regenerate in a ribonuclease solution or in pond water. Heads which had regenerated in ribonuclease displayed a retention level equal to that of head and tail sections which had regenerated in pond water. However, tails regenerated in ribonuclease performed randomly although they could be retrained to criterion.