Social contributions to meaning in life: the role of romantic relationship quality, parenting, and gender.

Introduction: The present study tests the association between romantic relationship quality and number of children on meaning in life (i.e., sense of purpose, coherence, and significance) and considers interactions between these constructs and gender.

Loss during COVID-19: Moderating effects of meaning and romantic relationships on anxiety and depressive symptoms.

Objective: The COVID-19 pandemic exacerbated experiences of loss and grief for many individuals and posed a challenging mental health crisis. Compared to studies examining a singular type of loss, the present study investigated the cumulative impacts of COVID-related losses on anxiety and depressive symptoms and examined whether meaning in life, marital status, or relationship quality offered a protective moderating role.

Method: A cross-sectional online survey was conducted approximately 1 year into the pandemic among 434 diverse individuals (32.

The birth of a story: Childbirth experiences, meaning-making, and postpartum adjustment.

The present study investigated how meaning-making around a birth experience predicts relationship quality and parenting stress across the transition to first-time parenthood, a time that many new parents find stressful and challenging. Childbirth experiences may set the stage for these challenges, and how new parents make meaning of childbirth could play a role in their subsequent postpartum adjustment. Meaning-making processes (sense making, benefit finding, and changes in identity) were coded from birth narratives collected from 77 mixed-sex biological parent dyads ( = 154 individuals) shortly after the birth of their first child.

Nonlinear Harmonic Distortion of Complementary Golay Codes.

Recent advances in electronics miniaturization have led to the development of low-power, low-cost, point-of-care ultrasound scanners. Low-cost systems employing simple bi-level pulse generation devices need only utilize binary phase modulated coded excitations to significantly improve sensitivity; however the performance of complementary codes in the presence of nonlinear harmonic distortion has not been thoroughly investigated. Through simulation, it was found that nonlinear propagation media with little attenuative properties can significantly deteriorate the Peak Sidelobe Level (PSL) performance of complementary Golay coded pulse compression, resulting in PSL levels of -62 dB using nonlinear acoustics theory contrasted with -198 dB in the linear case.

What happens when romantic couples discuss personal loss? Relational, emotional, and physiological impacts.

Does talking about loss with a romantic partner have salutary personal and relationship effects? Prior evidence reveals the benefits of emotional disclosure in couple relationships, yet disclosure about loss has been overlooked in research on couple communication. Using a novel communication paradigm with young-adult heterosexual romantic partners ( = 114 couples), we investigated emotions, physiological arousal (skin conductance responses [SCR]), and relationship closeness when narrating a personal loss and listening to the partner's loss, and compared these loss discussions to discussions about desired relationship changes. Based on partners' self-reports, narrating loss elicited more vulnerable and, unexpectedly, more antagonistic emotions.

Interpretation Bias in Breast Cancer Survivors Experiencing Fear of Cancer Recurrence.

Fear of cancer recurrence (FCR) is a prevalent and persistent challenge that many cancer survivors endure. While the role of interpretation bias, a tendency to perceive ambiguous situations as threatening, has been established in the onset and maintenance of FCR, few studies have examined cancer-related interpretation bias specifically. Grounded in the cognitive formulation of FCR, the current study aimed to fill this gap by investigating the relationship between cancer-related interpretation bias, FCR, and somatic symptoms, and examining whether bias mediates the relationship between somatic symptoms and FCR.

Physical touch during father-infant interactions is associated with paternal oxytocin levels.

Introduction: Physical connection, particularly parent-to-infant touch, is critical for the well-being of infants and may support the development of the parent-infant bond. Physical touch has also been found to stimulate oxytocin levels. This study tested whether fathers' micro-coded touch behaviors during parent-child interaction predicted their subsequent oxytocin levels.

Physiological linkage in pregnancy: Couples' cortisol, negative conflict behavior, and postpartum depression.

Within-couple concordance in momentary cortisol levels ("cortisol linkage") may reflect meaningful relationship dynamics. In this study, we examined couple cortisol linkage during pregnancy, associations with negative conflict couple behavior, and subsequent postpartum depressive symptoms. Eighty-two opposite-sex couples expecting their first child engaged in a conflict discussion, provided six salivary cortisol samples over the course of a laboratory visit, and then reported on depressive symptoms six months after their baby's birth.

Prenatal relationship conflict behavior predicts childbirth experiences and birth outcomes.

Despite evidence linking prenatal psychosocial stress and social support to perinatal maternal and infant health, no study has explored couple conflict behavior during pregnancy as a predictor of subsequent birth outcomes. The current study examines whether couples' positive and negative conflict behaviors during pregnancy predict their stress during the birth experience and gestational and birth outcomes. Forty-seven first-time expectant couples participated in a conflict discussion during pregnancy that was observationally coded.

Validity and reliability of metrics for translation of regional anaesthesia performance from cadavers to patients.

Background: Our goal is to develop metrics that quantify the translation of performance from cadavers to patients. Our primary objective was to develop steps and error checklists from a Delphi questionnaire. Our second objective was to show that our test scores were valid and reliable.

Enhanced Antibacterial and Antiadhesive Activities of Silver-PTFE Nanocomposite Coating for Urinary Catheters.

Catheter-associated urinary tract infection (CAUTI) presents a significant health problem worldwide and is associated with increased morbidity and mortality. Herein, a silver-polytetrafluoroethylene (Ag-PTFE) nanocomposite coating for catheters was developed via a facile wet chemistry method. Benefiting from the synergistic effect of Ag and PTFE, the as-prepared Ag-PTFE-coated catheter exhibited enhanced antibacterial and antiadhesive activities against two CAUTI-associated strains: WT F1693 and F1557.

In-vitro antibacterial and anti-encrustation performance of silver-polytetrafluoroethylene nanocomposite coated urinary catheters.

Background: Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections, leading to increased morbidity and mortality. A major reason for this is that urinary catheters are not yet capable of preventing CAUTIs.

Aim: To develop an anti-infective urinary catheter.

Young adult couples' behavioral and physiological responses to the infant simulator: A preliminary illustration of coparenting.

This exploratory application of the infant simulator with two couples is designed to illustrate individual reactivity and coparenting behaviors in young couples in serious relationships who do not yet have children. A 35-min protocol with standardized onsets and offsets of inconsolable baby cries was used to capture partner's individual behavioral and physiological responses as well as the couple's joint efforts to soothe the crying baby. Task feasibility was demonstrated by couples' persistent and wide-ranging efforts to calm the baby including rocking, feeding, changing, talking to the baby, and singing.

The weight of fatherhood: identifying mechanisms to explain paternal perinatal weight gain.

Men appear to gain weight during the transition to parenthood, and fathers are heavier than non-fathers. Paternal perinatal weight gain may set weight trajectories in midlife and have long-term health implications. Since men do not undergo the physical demands of pregnancy and breastfeeding, the specific mechanisms underlying weight gain in new fathers warrant investigation.

Investigation into the visual perceptive ability of anaesthetists during ultrasound-guided interscalene and femoral blocks conducted on soft embalmed cadavers: a randomised single-blind study.

Background: Errors may occur during regional anaesthesia whilst searching for nerves, needle tips, and test doses. Poor visual search impacts on decision making, clinical intervention, and patient safety.

Methods: We conducted a randomised single-blind study in a single university hospital.

MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa.

The mucus layer in the intestine affects several aspects of intestinal biology, encompassing physical, chemical protection, immunomodulation and growth, thus contributing to homeostasis. Mice with genetic inactivation of the gene, encoding the MUC2 mucin, the major protein component of mucus, exhibit altered intestinal homeostasis, which is strictly dependent on the habitat, likely due to differing complements of intestinal microbes. Our previous work established that deficiency was linked to low chronic inflammation resulting in tumor development in the small, large intestine including the rectum.

Investigation of Ultrasound-Measured Flow Velocity, Flow Rate and Wall Shear Rate in Radial and Ulnar Arteries Using Simulation.

Parameters of blood flow measured by ultrasound in radial and ulnar arteries, such as flow velocity, flow rate and wall shear rate, are widely used in clinical practice and clinical research. Investigation of these measurements is useful for evaluating accuracy and providing knowledge of error sources. A method for simulating the spectral Doppler ultrasound measurement process was developed with computational fluid dynamics providing flow-field data.

A pilot randomized controlled trial of cognitive bias modification to reduce fear of breast cancer recurrence.

Background: The most common, persistent concern among survivors of breast cancer is the fear that their disease will return, yet to the authors' knowledge, few interventions targeting fear of cancer recurrence (FCR) have been developed to date. The current pilot study examined the feasibility, acceptability, and preliminary efficacy of a home-delivered cognitive bias modification intervention to reduce FCR. The intervention, called Attention and Interpretation Modification for Fear of Breast Cancer Recurrence (AIM-FBCR), targeted 2 types of cognitive biases (ie, attention and interpretation biases).

Trainee anaesthetist diagnosis of intraneural injection-a study comparing B-mode ultrasound with the fusion of B-mode and elastography in the soft embalmed Thiel cadaver model.

Background: The incidence of intraneural injection during trainee anaesthetist ultrasound guided nerve block varies between 16% in experts and up to 35% in trainees. We hypothesized that elastography, an ultrasound-based technology that presents colour images of tissue strain, had the potential to improve trainee diagnosis of intraneural injection during UGRA, when integrated with B-Mode ultrasound onto a single image.

Methods: We recorded 40 median nerve blocks randomly allocated to 0.

Existential distress among caregivers of patients with brain tumors: a review of the literature.

Background: Attention to existential needs is a component of comprehensive oncologic care, and understanding these needs among informal caregivers of patients with brain tumors is necessary to provide them with comprehensive psychosocial care. The purpose of this systematic review was to synthesize the literature on existential distress experienced by these informal caregivers to inform the development of psychotherapeutic interventions for this population.

Methods: A systematic review was conducted using electronic medical databases.

The feasibility of micro-ultrasound as a tool to image peripheral nerves.

Despite widespread use of ultrasound imaging to guide needle placement, the incidence of transient and permanent nerve damage as a complication of regional anaesthesia has not changed over the last decade. In view of the controversy surrounding intraneural injection there is a need to understand the structural changes caused by subepineural and subperineural needle penetration. Clinical ultrasound machines do not provide adequate anatomical resolution, and anaesthetists have difficulty judging the precise location of the needle tip relative to the epineurium.

A study of the effect of clinical washing decontamination process on corrosion resistance of Martensitic Stainless Steel 420.

Corrosion of surgical instruments provides a seat for contamination and prevents proper sterilisation, placing both patients and medical staff at risk of infection. Corrosion can also compromise the structural integrity of instruments and lead to mechanical failure in use. It is essential to understand the various factors affecting corrosion resistance of surgical instruments and how it can be minimised.

Development of the Bereavement Risk Inventory and Screening Questionnaire (BRISQ): Item generation and expert panel feedback.

Objective: Following the loss of a loved one to cancer, a significant subset of bereaved family members are at heightened risk for mental and physical health problems; however, these family members often "fall through the cracks" of the healthcare system. A brief, clinically useful self-report bereavement risk-screening tool could facilitate more effective identification of family members in need of psychosocial support before and after a cancer loss. Thus, the purpose of this study was to develop and refine the Bereavement Risk Inventory and Screening Questionnaire (BRISQ), a self-report bereavement screening tool, and to assess its utility using feedback from bereavement experts.

Physical properties and functional alignment of soft-embalmed Thiel human cadaver when used as a simulator for ultrasound-guided regional anaesthesia.

Background: We evaluated the physical properties and functional alignment of the soft-embalmed Thiel cadaver as follows: by assessing tissue visibility; by measuring its acoustic, mechanical and elastic properties; by evaluating its durability in response to repeated injection; and by aligning images with humans.

Methods: In four soft-embalmed Thiel cadavers, we conducted three independent studies. We assessed the following factors: (i) soft tissue visibility in a single cadaver for 28 weeks after embalming; (ii) the displacement of tissues in response to 1 and 5 ml interscalene and femoral nerve blocks in a single cadaver; and (iii) the stiffness of nerves and perineural tissue in two cadavers.

Modelling and characterisation of a ultrasound-actuated needle for improved visibility in ultrasound-guided regional anaesthesia and tissue biopsy.

Clear needle visualisation is recognised as an unmet need for ultrasound guided percutaneous needle procedures including regional anaesthesia and tissue biopsy. With inadequate needle visibility, these procedures may result in serious complications or a failed operation. This paper reports analysis of the modal behaviour of a previously proposed ultrasound-actuated needle configuration, which may overcome this problem by improving needle visibility in colour Doppler imaging.