Publications by authors named "Cornelia Pocnet"

Article Synopsis
  • There is limited evidence regarding the traits of individuals with subjective cognitive decline (SCD) who also have amyloid positivity, which is related to Alzheimer's disease.
  • A study of 1640 participants showed that factors like age, clinical setting, and the presence of the APOE ε4 gene are linked to higher amyloid positivity, whereas education level also plays a role.
  • Specific SCD characteristics such as confirmed complaints and lack of depressive symptoms were associated with amyloid positivity, suggesting these traits can aid in identifying individuals who may have amyloid-related cognitive decline.
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In this paper, we highlighted links between personality traits and successful ageing through a systematic review of recent empirical studies. Particularly, we addressed the question of whether personality traits are related to successful ageing and, if so, why and how? Answers to this question provided, for example, arguments that supported personality's role in planning an individual's future based on self-knowledge, thereby contributing to a sense of identity throughout their life. Then, considering longitudinal studies, we examined whether personality is stable over one's life course, or does it change and, if so, why and under what conditions? Answers to this question gave substance to the idea that a stable personality allows for continuous and consistent development.

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The aim of this study was to investigate the relationship between personality traits, tobacco consumption, physical inactivity, obesity markers and metabolic components as cardiovascular risk factors (CVRFs). A total of 2543 participants from the general population (CoLaus|PsyCoLaus) had provided complete information on physical health and unhealthy behaviors and completed the Revised NEO Five-Factor Inventory. Our results show a strong cross-correlation between obesity markers and metabolic components suggesting that their combination could represent an important CVRF.

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Purpose: The aim of this study was to investigate the relationship between major recent life events that occurred during the last 5 years, social and personal resources, and subjective quality of life (QoL).

Methods: A total of 1801 participants from the general population (CoLaus/PsyCoLaus study) completed the Life Events Questionnaire, the Social Support Questionnaire, the NEO Five-Factor Inventory Revised, and the Manchester Short Assessment of Quality of Life.

Results: Major life events were modestly associated with the QoL (about 5 % of the explained variance).

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Background: Mild cognitive impairment (MCI) has been defined as a transitional state between normal aging and dementia. In many cases, MCI represents an early stage of developing cognitive impairment. Patients diagnosed with MCI do not meet the criteria for dementia as their general intellect and everyday activities are preserved, although minor changes in instrumental activities of daily living (ADL) may occur.

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Objective: The origins of behavioral and psychological symptoms (BPS) in Alzheimer's disease (AD) are still poorly understood. Focusing on individual personality structure, we explored the relationship between premorbid personality and its changes over 5 years, and BPS in patients at an early stage of AD.

Method: A total of 54 patients at an early stage of AD according to ICD-10 and NINCDS-ADRDA criteria and 64 control subjects were included.

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Objective: To investigate personality traits in patients with Alzheimer disease, compared with mentally healthy control subjects. We compared both current personality characteristics using structured interviews as well as current and previous personality traits as assessed by proxies.

Method: Fifty-four patients with mild Alzheimer disease and 64 control subjects described their personality traits using the Structured Interview for the Five-Factor Model.

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Clinical experience suggests that longstanding personality characteristics as a person's most distinctive features of all are likely to play a role in how someone with dementia copes with his increasing deficiencies. Personality characteristics may have a pathoplastic effect on both behavioral and psychological symptoms (BPS) or on cognition as well as cognitive decline. Cognitive disorders accompanied by BPS are a tremendous burden for both the patient and their proxies.

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