Publications by authors named "Cornelia Depner"
Background: The amino acid serine is an important substrate for biosynthesis and redox homeostasis. We investigated whether glioblastoma (GBM) cells are dependent on serine for survival under conditions of the tumour microenvironment.
Methods: Serine availability in GBM cells was modulated pharmacologically, genetically and by adjusting serine and glycine concentrations in the culture medium.
Article Synopsis
- Systems Biology focuses on understanding biological functions through the interactions of genes, proteins, and cells using experimental data, mathematical models, and computational simulations.
- A Masters-level education in Systems Biology is suggested to overcome hurdles related to a multidisciplinary approach and provide flexibility in curriculum and skill acquisition.
- The proposed framework includes skill definitions, customizable curricula, career paths, recruitment strategies, and collaboration mechanisms between academia and industry to enhance educational effectiveness and relevance.