Publications by authors named "Cornelia Cygon"
Article Synopsis
- The unfolded protein response (UPR) plays a key role in liver function, particularly how disturbances in the endoplasmic reticulum (ER) can disrupt metabolic balance.
- Creld2 is identified as a protein that helps manage stress responses in cells, enhancing protein folding and aiding recovery from ER stress.
- The absence of Creld2 leads to improper UPR regulation, resulting in liver fat accumulation, especially in males, indicating that chronic ER stress may contribute to liver diseases like fatty liver and steatohepatitis.
