Objective: To study the effects of depression and treatment with repetitive transcranial magnetic stimulation (rTMS) on sequence learning.
Background: Prefrontal dysfunction in depression may affect sequence learning and be amenable to normalization by rTMS.
Method: The serial reaction time test (SRTT) was administered to 19 patients with major depressive disorder (MDD) and 20 nondepressed control participants.
Objective: Two procedures for treating major depressive disorder were compared with regard to their respective effects on mood and cognition.
Background: Fourteen patients underwent treatment with electroconvulsive therapy and 14 underwent treatment with repetitive transcranial magnetic stimulation. Patients were tested on three occasions: before initiation of treatment, at the end of treatment, and 2 weeks after the end of treatment.