Publications by authors named "Corinne Leroi-Geissler"
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Synopsis of recent research by authors named "Corinne Leroi-Geissler"
- Corinne Leroi-Geissler's recent research primarily focuses on the development and optimization of novel antibacterial peptides, particularly those derived from myxobacteria, to combat multidrug-resistant infections.
- Her studies on the linear cationic lipopeptide des-acyl tridecaptins (DATs) highlight their in vitro and in vivo antibacterial activities, structural advantages, and mechanisms of action against pathogens.
- The optimization of the antibacterial properties and developability of the natural product Corramycin has led to advancements such as modifications to enhance membrane permeability, broaden antibacterial spectrum, and improve overall efficacy in murine models, showcasing promising therapeutic potential.
