Publications by authors named "Corinne Leget"
Article Synopsis
- Checkpoint blockade therapy is a promising cancer treatment, but not all patients benefit, highlighting the need for new targets.
- Blocking the KLRG1 receptor improves anti-tumor responses from NK cells and CD8 T cells, significantly reducing melanoma and breast cancer growth in mice.
- Combining KLRG1 blockade with PD-1 therapy enhances treatment effectiveness, leading to reduced tumor size and increased immune cell activation, even in tumors resistant to PD-1 therapy.
