Publications by authors named "Corinne Bani"
Article Synopsis
- Sulforaphane, derived from glucoraphanin found in broccoli sprouts, shows significant anti-inflammatory effects in a study with intestinal cells, while glucoraphanin itself appears inactive in this context.
- In celiac disease, persistent inflammation and oxidative stress affect the small intestine, making it crucial to explore compounds that could alleviate these conditions.
- The study indicates that sulforaphane modulates inflammatory responses and epithelial integrity during inflammatory conditions, suggesting glucoraphanin may also have more to offer than previously thought.
Article Synopsis
- Pigmented corn varieties are gaining attention for their health benefits, particularly their polyphenolic content, making them suitable for individuals with celiac disease who require gluten-free diets.
- The study analyzed the phenolic composition of two Italian pigmented corn varieties using HPLC-DAD, noting the presence of phenolic acids and anthocyanins, with minimal changes post-digestion.
- Results showed that extracts from these corns reduced inflammation markers in human intestinal cells and reversed oxidative stress effects, suggesting potential benefits for managing celiac disease inflammation through a gluten-free diet.
Celiac disease (CD) is an autoimmune disease. To date, the only universally recognized treatment for CD is the gluten-free diet (GFD). Despite the GFD, a state of inflammation and oxidative stress could remain at the intestinal level of celiac patients.
View Article and Find Full Text PDFInflammation and oxidative stress are two mechanisms involved in the pathogenesis of celiac disease (CD). Since the direct effect of gliadin on the intestinal epithelia is less studied, the aims of this study were the development of a specific cellular model based on the use of gliadin as a pro-inflammatory stimulus and the evaluation of the potential antioxidant and anti-inflammatory properties of extracts from different black rice in the framework of CD. The rice extracts were in vitro digested, characterized in terms of phenolic compounds and antioxidant capacity, and tested on Caco-2 cells to investigate their inhibitory effect on Reactive Oxygen Species, the NF-κB transcription and the CXC chemokines (sICAM-1, IL-8, and CXCL-10).
View Article and Find Full Text PDFCeliac disease is an autoimmune disorder that occurs in genetically predisposed individuals after consuming prolamins from some cereals. Although the products available for celiac subjects have increased significantly in quality and quantity over the last few decades, research still focuses on identifying new ingredients to improve the nutritional, sensorial and functional qualities of gluten-free products. In terms of toxicity for people with celiac disease, there is a wide variability between ancient and modern grains.
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