Intranasal corticosteroid users in The Netherlands: A drug utilization study.

Background: To improve (patient-tailored) instructions for intranasal corticosteroid (INC) administration, we need to gain insight into specific characteristics of INC users and comedication use.

Objective: We examined INC prescriptions obtained from the Dutch InterAction Database to gain insight into the prevalence and incidence rates, INC use in previous years, and comedication.

Methods: We retrospectively examined INC prescriptions written between January 1, 2015, and December 31, 2019.

Pharmacology, particle deposition and drug administration techniques of intranasal corticosteroids for treating allergic rhinitis.

This review presents an overview of the available literature regarding intranasal corticosteroids (INCs) for the treatment of allergic rhinitis (AR). Various treatment options exist for AR including INCs, antihistamines and leucotriene antagonists. INCs are considered to be the most effective therapy for moderate-to-severe AR, as they are effective against nasal and ocular symptoms and improve quality of life.

Adverse Drug Reactions of Intranasal Corticosteroids in the Netherlands: An Analysis from the Netherlands Pharmacovigilance Center.

Background: Intranasal corticosteroids are one of the cornerstone treatment options for allergic rhinitis and chronic sinusitis complaints. Safety information in the summary of product characteristics may not be representative for observations in daily clinical practice. The Netherlands Pharmacovigilance Center (Lareb) collects post-marketing safety information, using spontaneous reporting systems.

Improved quality of reporting safety data of medication in paediatric randomised controlled trials.

Objective: Evaluating the reporting of safety data of medication in paediatric randomised controlled trials (RCTs) in 2017-2018 compared with our earlier study.

Design: Literature search with a systemic appraisal of adverse drug event reporting.

Main Outcome Measures: Quality of reporting of safety data using Consolidated Standards of Reporting Trials (CONSORT) and Ioannidis scores in paediatric drug RCTs.

The Quality of Instructional YouTube Videos for the Administration of Intranasal Spray: Observational Study.

Background: Allergic rhinitis is a common disorder affecting both children and adults. Recommended treatment consists of intranasal corticosteroid spray administration, but only few patients administer the nasal spray in the correct technical manner. A wrong administration technique may result in side effects and affect the efficacy and adherence, thus making accurate administration instructions indispensable.

Observational study of administering intranasal steroid sprays by healthcare workers.

Objectives: Patients with allergic rhinitis receive their information about administering intranasal corticosteroid sprays (INCS) from healthcare workers. Since the majority of patients does not administer these sprays correctly, we investigated whether healthcare workers know how to administer INCS.

Settings: We studied participants at their working place: pharmacy, outpatient clinic or general practitioner centre for emergencies.

An age-adjusted instruction video enhances the correct use of nasal corticosteroid sprays in children.

Introduction And Objectives: Allergic rhinitis is a common disorder. Intranasal corticosteroid sprays are used to control symptoms. However, incorrect use of these sprays can decrease efficacy and lead to side effects such as nose bleeding.

Inadequate quality of administration of intranasal corticosteroid sprays.

Purpose: Considering the fact that many mistakes are still being made by asthmatic patients when inhaling lung medication, it is important to gain insight into current techniques used to administer intranasal corticosteroid sprays (INCS) in allergic rhinitis patients. In this study, we aimed to get insight into daily use of INCS and to determine if improvement of the technique is required.

Patients And Methods: A checklist, based on available patient information leaflets (PILs) and literature, was used to determine the participants' application of the techniques used to administer INCS.

Evaluation of instructions in patient information leaflets for the use of intranasal corticosteroid sprays: an observational study.

Objectives: In this study, we analysed patient information leaflets (PILs) of intranasal corticosteroid sprays (INCS) of different manufacturers in the UK to determine if instructions for the use of INCS are complete and uniform.

Setting: PILs of all INCS of all manufacturers, available for patients in the UK, were collected from the British National Formulary website and the Medicines and Healthcare products Regulatory Agency website. All instructions in these PILs were analysed.