Plackett-Burman design in the biosynthesis of silver nanoparticles with (Chinchircoma) and preliminary evaluation of its antibacterial activity.

The aim of this study was to synthesize silver nanoparticles (AgNPs) using the methanolic fraction of leaves using Plackett-Burman design to optimize process parameters and to evaluate its antibacterial effect. For the separation of phytoconstituents, chromatographic techniques were used. For characterization and identification, UV - VIS spectrophotometry, FTIR spectrophotometry, Dynamic Light Scattering (DLS) and transmission electron microscopy (TEM) were used.

Biochemical and hemostatic description of a thrombin-like enzyme TLBro from snake venom.

The current study's objective is to characterize a new throm-bin-like enzyme called TLBro that was obtained from snake from a biochemical and hemostatic perspective. One chromatographic step was used to purify it, producing the serine protease TLBro. Molecular mass was estimated by SDS-PAGE to be between reduced and unreduced by 35 kDa.

[Anti-Inflammatory Effect of The Flavonoid Fraction of Lepechinia meyenii (Walp.) Epling (SAGE) on Leukocytes of Patients With Rheumatoid Arthritis].

Objectives: to assess the anti-inflammatory effect of the flavonoid fraction of Lepechinia meyenii (Walp.) Epling on leukocytes of patients with rheumatoid arthritis (RA).

Materials And Methods: Plants of the species Lepechinia meyenii (Walp.