Publications by authors named "Corina Delia"

Article Synopsis
  • Familial hypercholesterolemia (FH) is an underdiagnosed genetic condition that increases the risk of early cardiovascular issues, highlighting the need for early interventions in children.
  • An interventional study with 10 patients showed that those without FH achieved significant lipid level improvements through lifestyle changes alone, while genetically confirmed FH patients did not see similar benefits without medication.
  • The study emphasizes the critical role of genetic testing for FH in guiding treatment decisions, as it may not be routinely included in current screening practices.
View Article and Find Full Text PDF

There is an increasing interest in dyslipidemia in adult patients since it is known to contribute to early cardiovascular disease. Often, dyslipidemia starts in childhood, and it is associated with aggravating lifestyle choices concerning eating habits, such as the tendency to consume processed food and fast food, as well as the tendency to be more and more sedentary. We conducted a retrospective cross-sectional study describing the prevalence of dyslipidemia in a single medical center in Romania and the associated pathology.

View Article and Find Full Text PDF
Article Synopsis
  • Familial hypercholesterolemia (FH) is a genetic disorder leading to high LDL-cholesterol, increasing risks of cardiovascular issues later in life, particularly in adults.
  • A study tested 20 Romanian children with elevated LDL-cholesterol levels at a specialized health institute, using the Illumina TruSight Cardio panel for genetic analysis.
  • Results showed that 5 out of 20 patients had identifiable pathogenic genetic variants linked to FH, indicating that early diagnosis through lipid screening could be crucial for prevention.
View Article and Find Full Text PDF
Article Synopsis
  • * All 47 elements were found in brain tumor tissue, with 22 detected in over 80% of samples, indicating their ability to cross the blood-brain barrier.
  • * Notably, higher median blood levels of cadmium, lead, and nickel, along with significant concentrations of gadolinium and tantalum in patients, suggest that various elements used in tech devices may influence brain tumor development.
View Article and Find Full Text PDF

Biomonitoring studies are important for quantifying the body burden of pollutants and their possible effects on health. Serum concentration of 42 elements was assessed by ICP-MS in 89 children (7.2 ± 3.

View Article and Find Full Text PDF

It is known that cigarette smoking is correlated with medical associated inquires. New electronic cigarettes are intensively advertised as an alternative to conventional smoking, but only a few studies demonstrate their harmful potential. A cross-sectional study was designed using 150 subjects from Brasov (Romania), divided into three groups: non-smokers (NS = 58), conventional cigarettes smokers (CS = 58) and electronic cigarettes users (ECS = 34).

View Article and Find Full Text PDF

Introduction: Atypical antipsychotics have significantly improved the quality of life for schizophrenic patients. Despite their beneficial effects, these antipsychotics induce weight gain, diabetes, and dyslipidemia. The aims of this study were to investigate the antioxidative activity of paraoxonase and assess lipid profile as a cardiovascular risk factor in patients with schizophrenia under long-term clozapine or risperidone treatment.

View Article and Find Full Text PDF