The Value of Total Knee Replacement in Patients With Knee Osteoarthritis and a Body Mass Index of 40 kg/m or Greater : A Cost-Effectiveness Analysis.

Background: Total knee replacement (TKR) is an effective and cost-effective strategy for treating end-stage knee osteoarthritis. Greater risk for complications among TKR recipients with a body mass index (BMI) of 40 kg/m or greater has raised concerns about the value of TKR in this population.

Objective: To assess the value of TKR in recipients with a BMI of 40 kg/m or greater using a cost-effectiveness analysis.