Focus on focus: lack of coherence between systemic and microvascular indices of oedema formation.

Background: Fluid therapy remains a cornerstone of therapy in shock states. However, fluid overloading ultimately results in oedema formation which is related to excess morbidity and mortality. Handheld microscopes are now frequently used to study the sublingual microcirculation.

No evidence for distinguishing bacterial from viral acute rhinosinusitis using symptom duration and purulent rhinorrhea: a systematic review of the evidence base.

Objective: To evaluate the diagnostic value of symptom duration and purulent rhinorrhea in adults suspected of having acute bacterial rhinosinusitis.

Data Sources: PubMed, EMBASE, and the Cochrane Library.

Review Methods: We performed a comprehensive systematic search on March 28, 2013.