Publications by authors named "Coric D"

Objective: Cervical spondylotic myelopathy (CSM) shows varying levels of improvement after surgical treatment. While some patients improve soon after surgery, others may take months to years to show any signs of improvement. The goal of this study was to evaluate postoperative improvement, patient-reported outcomes, and patient satisfaction up to 2 years after surgical treatment for CSM, which will help optimize the current treatment strategies and effectively manage patient expectations.

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Background: Certain demographics and/or risk factors contribute to complications following cervical spinal surgery including pseudarthrosis, prolonged pain, and reduced quality of life (QoL). Pulsed electromagnetic field (PEMF) stimulation is a non-invasive therapy that may enhance fusion success in at-risk patients.

Objective: To evaluate the safety and efficacy of post-operative adjunctive PEMF therapy following cervical spinal surgery in subjects at risk for pseudarthrosis.

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Article Synopsis
  • The study explores the impact of revision surgery on patient-reported outcomes (PROs) following initial surgeries for grade 1 spondylolisthesis, comparing decompression-only and decompression plus fusion (D+F) treatments.
  • Data was collected from over 600 patients, revealing that 13.3% of decompression-only patients and 9.8% of D+F patients required revision surgery within 5 years, with revision patients reporting worse outcomes.
  • The findings indicate that while revision surgery affects PROs adversely, patients undergoing D+F see a more significant decline in their reported outcomes compared to those who only had decompression surgery.
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Objective: The aim of this study was to compare the rate of achievement of the minimal clinically important difference (MCID) in patient-reported outcomes (PROs) and satisfaction between cervical spondylotic myelopathy (CSM) patients with and without class III obesity who underwent surgery.

Methods: The authors analyzed patients from the 14 highest-enrolling sites in the prospective Quality Outcomes Database CSM cohort. Patients were dichotomized based on whether or not they were obese (class III, BMI ≥ 35 kg/m2).

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Article Synopsis
  • The study aimed to explore the long-term effects of body mass index (BMI) on surgical outcomes in patients with low-grade lumbar spondylolisthesis, specifically comparing obese (BMI ≥ 35) and nonobese (BMI < 35) patients.
  • Among 608 patients studied, those with a BMI ≥ 35 were generally younger, reported more severe pain and disability at baseline, and had a higher likelihood of requiring fusion surgery compared to their nonobese counterparts.
  • Five years after surgery, no significant differences were found in readmission rates or reoperation rates between the BMI groups, although higher BMI was linked to lower chances of achieving important clinical improvements post-surgery.
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Background: Cervical disc arthroplasty is a well-established alternative to anterior cervical fusion but requires precise placement for optimal outcomes. We present the case of a 2-level cervical disc arthroplasty with suboptimal implantation of the interbody devices, requiring revision corpectomy. Supplemental video, Supplemental Digital Content 1 ( http://links.

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Objective: Depression and anxiety are associated with poor outcomes following spine surgery. However, the influence of these conditions on achieving a minimal clinically important difference (MCID) following lumbar spine surgery, as well as the potential compounding effects of comorbid depression and anxiety, is not well understood. This study explores the impact of comorbid depression and anxiety on long-term clinical outcomes following surgical treatment for degenerative lumbar spondylolisthesis.

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Objective: Myelopathy in the cervical spine can present with diverse symptoms, many of which can be debilitating for patients. Patients with radiculopathy symptoms demonstrate added complexity because of the overlapping symptoms and treatment considerations. The authors sought to assess outcomes in patients with myelopathy presenting with or without concurrent radiculopathy.

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Objective: Lumbar decompression and/or fusion surgery is a common operation for symptomatic lumbar spondylolisthesis refractory to conservative management. Multiyear follow-up of patient outcomes can be difficult to obtain but allows for identification of preoperative patient characteristics associated with durable pain relief, improved functional outcome, and higher patient satisfaction.

Methods: A query of the Quality Outcomes Database (QOD) low-grade spondylolisthesis module for patients who underwent surgery for grade 1 lumbar spondylolisthesis (from July 2014 to June 2016 at the 12 highest-enrolling sites) was used to identify patient satisfaction, as measured with the North American Spine Society (NASS) questionnaire, which uses a scale of 1-4.

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Aluminium finds wide application in mechanical engineering due to its low density and corrosion resistance. In this research, aluminium was subjected to two different metal forming technologies-cold forging (upsetting) and equal channel angular pressing (ECAP)-to obtain improvement in its exploitation properties. Parallel to changing mechanical properties by using these two processes, there was a change in the microstructure of the material.

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Study Design: Prospective trial comparing the investigation group to propensity-matched historic control group.

Objective: To evaluate five-year results of single-level PEEK-on-ceramic cervical total disc replacement (TDR) compared with a propensity-matched anterior cervical discectomy and fusion (ACDF) control group.

Summary Of Background Data: Cervical TDR has gained acceptance as a treatment for symptomatic disk degeneration.

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Objective: Posterior lumbar interbody fusion (PLIF) and/or transforaminal lumbar interbody fusion (TLIF), referred to as "PLIF/TLIF," is a commonly performed operation for lumbar spondylolisthesis. Its long-term cost-effectiveness has not been well described. The aim of this study was to determine the 5-year cost-effectiveness of PLIF/TLIF for grade 1 degenerative lumbar spondylolisthesis using prospective data collected from the multicenter Quality Outcomes Database (QOD).

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Objective: Patients with cervical spondylotic myelopathy (CSM) experience progressive neurological impairment. Surgical intervention is often pursued to halt neurological symptom progression and allow for recovery of function. In this paper, the authors explore predictors of patient satisfaction following surgical intervention for CSM.

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Article Synopsis
  • This study is a retrospective analysis of data collected from patients who underwent surgery for low grade spondylolisthesis, aiming to identify factors that predict delayed improvement post-surgery.
  • Among the 436 patients included, most experienced quick clinical enhancements, but about 21.4% showed delayed recovery, reaching the minimal clinically important difference (MCID) at 12 months rather than 3 months.
  • Key factors linked to this delayed improvement were poorer pre-surgery walking ability, better initial pain scores, and worse leg pain scores at the 3-month mark.*
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Background: Thoracolumbar fractures (TLF) requiring surgical intervention can be treated with either open or percutaneous stabilization, each with some distinct risks and benefits. There is insufficient evidence available to support one approach as superior.

Methods: Patients who underwent spinal fixation for TLF between 2008 and 2020 were reviewed.

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Background: Progenitor cells derived from intervertebral disc tissue demonstrated immunomodulatory and regenerative properties in preclinical studies. We report the safety and efficacy results of a US Food and Drug Administration-approved clinical trial of these cells for the treatment of symptomatic degenerative disc disease.

Methods: Sixty patients with symptomatic single-level lumbar degenerative disc disease (mean age 37.

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Objective: Deficiency in patient education has been correlated with increased disease-related morbidity and decreased access to care. However, the associations between educational level, preoperative disease severity, and postoperative outcomes in patients with lumbar spondylolisthesis have yet to be explored.

Methods: The spondylolisthesis dataset of the Quality Outcomes Database (QOD)-a cohort with prospectively collected data by the SpineCORe study team of the 12 highest enrolling sites with an 81% follow-up at 5 years -was utilized and stratified for educational level.

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The heat treatment of aluminum alloys is very important in industries where low weight in combination with high wear resistance, good strength, and hardness are important. However, depending on their chemical composition, aluminum alloys are subjected to different mechanical and thermal treatments to achieve the most favorable properties. In this study, an Al-Zn-Mg alloy was heat-treated including solution annealing at 490 °C for 1 h with subsequent artificial aging at 130, 160, and 190 °C for 1, 5, and 9 h.

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Background: The comparative effectiveness of decompression plus lumbar facet arthroplasty versus decompression plus instrumented lumbar spinal fusion in patients with lumbar spinal stenosis and grade-I degenerative spondylolisthesis is unknown.

Methods: In this randomized, controlled, Food and Drug Administration Investigational Device Exemption trial, we assigned patients who had single-level lumbar spinal stenosis and grade-I degenerative spondylolisthesis to undergo decompression plus lumbar facet arthroplasty (arthroplasty group) or decompression plus fusion (fusion group). The primary outcome was a predetermined composite clinical success score.

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Study Design: Retrospective analysis of a prospective, multicenter registry.

Objective: To assess whether upper or lower limb mJOA improvement more strongly associates with patient satisfaction after surgery for cervical spondylotic myelopathy (CSM).

Summary Of Background Data: The modified Japanese Orthopaedic Association (mJOA) is commonly used to assess functional status in patients with CSM.

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Study Design: A prospective multicenter clinical trial (NCT03177473) was conducted with a retrospective cohort used as a control arm.

Objective: The purpose of this study was to evaluate cervical spine fusion rates in subjects with risk factors for pseudarthrosis who received pulsed electromagnetic field (PEMF) treatment.

Summary Of Background Data: Certain risk factors predispose patients to pseudarthrosis, which is associated with prolonged pain, reduced function, and decreased quality of life.

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Article Synopsis
  • The study aimed to compare outcomes between two surgical procedures—posterior foraminotomy and anterior cervical discectomy and fusion (ACDF)—for patients with cervical radiculopathy, focusing on both clinical results and patient-reported outcomes (PROs).
  • Researchers analyzed data from 7,805 patients, matching 216 who had posterior foraminotomy to 1,080 who had ACDF based on 29 variables.
  • Results showed that while both procedures were similar in PROs, ACDF had higher patient satisfaction, shorter hospital stays were associated with posterior foraminotomy, and it also faced higher reoperation rates within a year.
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Various foaming agents can be used to achieve foaming of the precursors obtained by using the powder metallurgy method. However, the thermal behavior of pure aluminum precursors with different foaming agents has been studied very little in recent times. For the production of aluminum foams with closed cells, 1 wt.

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Objective: There is a lack of strong evidence for use of expensive bone substitutes. This study compares perioperative data and patient reported quality-of-life outcomes across the varied types of bone graft extenders. The study analyzes the existing Quality and Outcomes Database and evaluates patient reported outcomes for 1-3 level lumbar fusion procedures comparing across different types of biologics bone graft.

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Objective: Cervical spondylotic myelopathy (CSM) can cause significant difficulty with driving and a subsequent reduction in an individual's quality of life due to neurological deterioration. The positive impact of surgery on postoperative patient-reported driving capabilities has been seldom explored.

Methods: The CSM module of the Quality Outcomes Database was utilized.

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