Publications by authors named "Corey Hartman"

Melasma is a highly recurrent disorder that is challenging to treat and significantly affects the quality of life of patients. Cysteamine is an endogenous antioxidant produced during the coenzyme A metabolism cycle and is naturally present in all mammalian cells. The depigmenting efficacy of topical cysteamine has been shown in several double-blind, randomized, placebo-controlled clinical trials.

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Article Synopsis
  • A study reviewing sunscreen-related publications found that only 5.3% of the 5,927 articles specifically addressed skin of color (SOC) despite the growing awareness of this issue since 2007.
  • The majority of SOC articles focus on sunscreen knowledge and patient behaviors (29%), with only a small fraction (5%) reporting clinical trials; common conditions discussed include melasma and post-inflammatory hyperpigmentation.
  • Although articles on SOC increased in 2022, the overall gap in research highlights the need for more evidence to support discussions on sunscreen use among darker skin types in clinical settings.
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Objective: There are clinical differences in healthy skin requirements and skin-aging features by race and ethnicity. However, individuals of color are underrepresented in dermatology-related medical information. We sought to gather information from women of color regarding their attitudes about the importance of the prevention of skin aging, available information, and perception of representation in skin-aging prevention information.

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Article Synopsis
  • Cysteamine isobionic-amide, a new depigmenting agent, was tested against the gold standard treatment, Modified Kligman's formula (mKF), for melasma in a clinical trial involving 80 patients.
  • Both treatments demonstrated equivalent effectiveness in reducing melasma severity at weeks 4 and 16, but cysteamine showed significantly higher patient satisfaction and quality of life improvements.
  • The study suggests that cysteamine isobionic-amide is a promising alternative to mKF for long-term melasma treatment, offering a faster onset of action and fewer side effects.
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Background: Retinoids and alpha- and beta hydroxy acids are common components utilized in regimens for blemish-prone skin. However, balancing efficacy and tolerability is often challenging.

Patients/methods: This pilot study evaluated a double-conjugated retinoid serum specifically formulated for blemish-prone skin (AHARet-SA) in combination with exfoliating peel pads (double-conjugated retinoid, glycolic, lactic, and salicylic acids), a cleanser, mineral-based sunscreen, and a lightweight moisturizer in female participants with mild-to-moderate blemish-prone skin.

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  • The treatment of dark circles and under-eye puffiness is complex and there's a need for better skincare solutions that are effective for diverse patients.
  • A study tested a new eye cream, MTEC, which includes ingredients like vitamin C, peptides, and caffeine, to see if it could improve these issues by targeting skin health and pigmentation.
  • Results showed that the MTEC significantly improved the appearance of dark circles and puffiness among various participants, making it a promising treatment option.
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Background: The efficacy and safety of an over-the-counter (OTC) 1% colloidal oatmeal cream versus a ceramide-based prescription barrier cream in children with mild-to-moderate atopic dermatitis (AD) were previously described.

Objectives: Here, findings are reported for the Black/African American subgroup.

Methods: Patients were randomized to 1% oatmeal cream or prescription barrier cream twice daily or as needed for three weeks.

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Background: There is a lack of diversity in dermatology regarding skin of color-related content. This has negative implications for patients of color and continues to be a hurdle to providing proper care to these patient populations. As patients increasingly look to the internet as a resource to gain insight on dermatologic conditions and potential treatment options, the information presented must be accurate and informational.

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  • * The 2022 Acne Management Consensus Roundtable highlighted advancements since the last guidelines in 2016, focusing on the role of androgens and the new topical anti-androgen clascoterone.
  • * Clascoterone, approved by the FDA in 2020 for those 12 and older, offers a novel treatment approach and aims to address significant gaps in current acne management practices.
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Cysteamine is an aminothiol naturally present in cells of the human body as an antioxidant resulting from the degradation of Coenzyme A. Physiologically it is well distributed in mammalian tissues. Highly concentrated in human milk, cysteamine acts as an intrinsic antioxidant and is known for its protective role.

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Several theoretical perspectives suggest that knowledge of children's perceptions of and beliefs about their parents' depression may be critical for understanding its impact on children. This paper describes the development and preliminary evidence for the psychometric properties of a new measure, the Children's Perceptions of Others' Depression - Mother Version (CPOD-MV), which assesses theoretically and empirically driven constructs related to children's understanding and beliefs about their mothers' depression. These constructs include children's perceptions of the severity, chronicity, and impairment of their mothers' depression; self-blame for their mother's depression; and beliefs about their abilities to deal with their mother's depression.

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