Melasma is a highly recurrent disorder that is challenging to treat and significantly affects the quality of life of patients. Cysteamine is an endogenous antioxidant produced during the coenzyme A metabolism cycle and is naturally present in all mammalian cells. The depigmenting efficacy of topical cysteamine has been shown in several double-blind, randomized, placebo-controlled clinical trials.
View Article and Find Full Text PDFObjective: There are clinical differences in healthy skin requirements and skin-aging features by race and ethnicity. However, individuals of color are underrepresented in dermatology-related medical information. We sought to gather information from women of color regarding their attitudes about the importance of the prevention of skin aging, available information, and perception of representation in skin-aging prevention information.
View Article and Find Full Text PDFBackground: Retinoids and alpha- and beta hydroxy acids are common components utilized in regimens for blemish-prone skin. However, balancing efficacy and tolerability is often challenging.
Patients/methods: This pilot study evaluated a double-conjugated retinoid serum specifically formulated for blemish-prone skin (AHARet-SA) in combination with exfoliating peel pads (double-conjugated retinoid, glycolic, lactic, and salicylic acids), a cleanser, mineral-based sunscreen, and a lightweight moisturizer in female participants with mild-to-moderate blemish-prone skin.
Background: The efficacy and safety of an over-the-counter (OTC) 1% colloidal oatmeal cream versus a ceramide-based prescription barrier cream in children with mild-to-moderate atopic dermatitis (AD) were previously described.
Objectives: Here, findings are reported for the Black/African American subgroup.
Methods: Patients were randomized to 1% oatmeal cream or prescription barrier cream twice daily or as needed for three weeks.
Background: There is a lack of diversity in dermatology regarding skin of color-related content. This has negative implications for patients of color and continues to be a hurdle to providing proper care to these patient populations. As patients increasingly look to the internet as a resource to gain insight on dermatologic conditions and potential treatment options, the information presented must be accurate and informational.
View Article and Find Full Text PDFCysteamine is an aminothiol naturally present in cells of the human body as an antioxidant resulting from the degradation of Coenzyme A. Physiologically it is well distributed in mammalian tissues. Highly concentrated in human milk, cysteamine acts as an intrinsic antioxidant and is known for its protective role.
View Article and Find Full Text PDFSeveral theoretical perspectives suggest that knowledge of children's perceptions of and beliefs about their parents' depression may be critical for understanding its impact on children. This paper describes the development and preliminary evidence for the psychometric properties of a new measure, the Children's Perceptions of Others' Depression - Mother Version (CPOD-MV), which assesses theoretically and empirically driven constructs related to children's understanding and beliefs about their mothers' depression. These constructs include children's perceptions of the severity, chronicity, and impairment of their mothers' depression; self-blame for their mother's depression; and beliefs about their abilities to deal with their mother's depression.
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