Publications by authors named "Coralie La Marca"
Anti-AGO1 Antibodies Identify a Subset of Autoimmune Sensory Neuronopathy.
Christian P Moritz Yannick Tholance Pierre-Baptiste Vallayer Le-Duy Do Sergio Muñiz-Castrillo Coralie La Marca
Neurol Neuroimmunol Neuroinflamm
May 2023
Background And Objectives: Autoantibodies (Abs) improve diagnosis and treatment decisions of idiopathic neurologic disorders. Recently, we identified Abs against Argonaute (AGO) proteins as potential autoimmunity biomarkers in neurologic disorders. In this study, we aim to reveal (1) the frequency of AGO1 Abs in sensory neuronopathy (SNN), (2) titers and IgG subclasses, and (3) their clinical pattern including response to treatment.
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- Scientists found that autoantibodies (Abs) can help diagnose diseases and are important for deciding treatments.
- They tested 434 patients with nerve issues and others to see if they had specific antibodies against a protein called AGO.
- Out of those tested, 44 had antibodies, with most being from patients with nerve problems or autoimmune diseases, but none from healthy people. *