Publications by authors named "Cooper Nyirenda"

The emergence and spread across sub-Saharan Africa of Plasmodium falciparum resistant to the inexpensive antimalarials chloroquine and sulfadoxine-pyrimethamine has worsened the health and hampered the socio-economic development of affected countries, a situation that calls for urgent review of malaria treatment policies in these countries. The Roll Back Malaria (RBM) initiative promotes strong partnerships for implementing effective malaria control measures. The development of clear policies to guide such implementation at country level offers a way of assessing the achievement of set milestones in this collaborative venture.

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Article Synopsis
  • The study evaluated the effectiveness of antiretroviral therapy (ART) at Queen Elizabeth Central Hospital in Malawi, focusing on a fixed drug combination of stavudine, lamivudine, and nevirapine.
  • Out of 422 patients on ART since 2000, 59% were lost to follow-up, but the 176 patients included in the study showed good clinical results and high nevirapine plasma levels associated with effective treatment.
  • Non-adherence mainly stemmed from drug shortages and financial issues, highlighting the need for consistent, free drug supplies to improve patient retention and adherence.
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