[Prehospital non-invasive ventilation in Germany: results of a nationwide survey of ground-based emergency medical services].

Background And Objectives: Non-invasive ventilation (NIV) is an evidence-based treatment of acute respiratory failure and can be helpful to reduce morbidity and mortality. In Germany national S3 guidelines for inhospital use of NIV based on a large number of clinical trials were published in 2008; however, only limited data for prehospital non-invasive ventilation (pNIV) and hence no recommendations for prehospital use exist so far.

Aim: In order to create a database for pNIV in Germany a nationwide survey was conducted to explore the status quo for the years 2005-2008 and to survey expected future developments including disposability, acceptance and frequency of pNIV.

Familial risk for depression and p3b component as a possible neurocognitive vulnerability marker.

Objective: Complex genetic mechanisms are involved in the vulnerability to depressive disorders and cognitive dysfunctions found in depression. This study was performed to explore the effect of the familial risk for depression on electrophysiological correlates of attentional functions as demonstrated by an event-related potential (ERP) go/no-go experiment.

Methods: The component P3b as an indicator of target detection processing was investigated in two groups of healthy subjects with or without a family history of depression (n = 14 each).

Today's and Tomorrow's Instruments.

This article will discuss the importance of Raimond Castaing's thesis on the genesis of a nondestructive and truly quantitative microanalytical method that assisted the scientific community in moving forward in the development of microanalytical instruments. I will also share with you my recollection of the decades of improvement in the electron probe microanalyzer (EPMA), that has allowed us to reach our present level of instrument sophistication, and I will explore with you my thoughts on the future evolution of this technique. To conclude, I will present the current status of related microanalysis techniques developed under Castaing in Orsay in the 1960s, as Castaing's interest in microanalysis was not limited to electron probe microanalysis alone.