Validation of the World Health Organization's Disability Assessment Schedule 2.0 for children with mental disorders in specialized health-care services.

Introduction: Mental disorders are highly prevalent among children, yet access to timely and effective treatment remains limited. Untreated or poorly managed mental disorders in children are associated with significant functional deterioration and long-term consequences. The validation of reliable assessment tools is crucial for identifying functional impairments and guiding interventions in this population.

Association of alcohol-metabolizing genes with alcoholism in a Mexican Indian (Otomi) population.

Association studies provide a powerful approach to link DNA variants and genetic predisposition to complex diseases. In this study, we determined the genotype and allelic frequencies of genes encoding enzymes involved in alcohol metabolism in alcoholic and nonalcoholic subjects of related ethnicity. A total of 118 individuals of Otomi Mexican Indian ancestry were included.