Publications by authors named "Constantin Mayer"

Background: Return to sport testing is an established routine, especially for athletes who have ruptured their anterior cruciate ligament (ACL). Various tests are performed, often combined in test batteries, such as the Back-in-action (BIA) test battery. Unfortunately, pre-injury performance is often unknown, and only few athletes pass the high demands of these test batteries.

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Article Synopsis
  • - Bone-tendon junctions are weak points prone to injury, especially in young males, with the tibial tubercle being a key area susceptible to conditions like Osgood Schlatter disease from chronic trauma.
  • - While repetitive trauma leads to conditions like OSD in kids, adults typically face issues like distal patellar tendon ruptures around their 30s-40s.
  • - This text presents a rare case of a 15-year-old soccer player who experienced a fracture of the tibial tubercle and a simultaneous rupture of the patellar tendon, alongside a review of related medical literature.
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Inline skater hockey is a sport originating from ice hockey, which is practised in Germany by about 6000 athletes. There are some differences to ice hockey, which lead to a special risk profile of the athletes.All 315 active players of the First German Inline Skater Hockey League in the years 2018 and 2019 were contacted to participate in an online survey.

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Purpose: Orthopaedic scores are essential for the clinical assessment of movement disorders but require an experienced clinician for the manual scoring. Wearable systems are taking root in the medical field and offer a possibility for the convenient collection of motion tracking data. The purpose of this work is to demonstrate the feasibility of automated orthopaedic scorings based on motion tracking data using the Harris Hip Score and the Knee Society Score as examples.

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The return to sport after knee injury is challenging. This is burdensome for sports with a high incidence of injuries, such as team handball. Various tests guide decision making, but often the athlete's preinjury performance of these measures remains unknown.

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Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study gives an overview of the current available surface-coated bone substitutes and provides an outlook for future perspectives.

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Handball is one of the most traumatic sports. The knee is the most commonly injured joint. To prevent knee injuries, optimal functional knee stability is of great importance.

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Purpose: Despite the great evolvement of sports medicine, there is still a lack of consensus among sports physicians regarding the decision of return to sports after knee injury, especially in non-elite sports. Currently, no sport-specific reference data for an objective reliable evaluation of functional knee stability exist. The purpose of this study was to assess objective measures on knee joint stability from an established test battery in non-elite handball.

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Various studies in recent years have shown that, within ball sports, handball players have a high risk of accidents and injuries. The knee joint is the most frequently injured body region, and ruptures of the anterior cruciate ligament the most common injury to the knee. To prevent consequential damage or recurrent knee injury, good functional stability of the knee is of high importance.

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Purpose: The tensiomyography (TMG) technique is increasingly used to determine muscle contractile properties in exercise and injury management. The present study investigated the informative value of TMG parameters in correlation with commonly used (creatine kinase, CK; myoglobin, Mb) and novel candidate biomarkers of muscle damage (heart-type fatty acid-binding protein, h-FABP; high-mobility group box 1, HMGB1).

Methods: Ten untrained men performed 6 × 10 eccentric contractions of the elbow flexors at 110% of the concentric one repetition maximum.

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Article Synopsis
  • Osteoarthritis (OA) is a common joint disorder that negatively affects the quality of life due to chronic pain and decreased mobility, with known risk factors including age, obesity, and prior injuries, but its specific molecular mechanisms remain unclear.
  • A study involving 69 patients categorized them into an osteoarthritis group and two control groups, collecting samples from their joints to analyze markers of oxidative and nitrosative stress related to degenerative processes.
  • Results indicated slight inflammation across all groups, but significantly higher levels of the oxidative stress marker (8-isoprostane F2α) were found in OA patients compared to controls, suggesting a potential link between oxidative stress and OA severity.
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Objective: Mixed martial arts (MMA) is a combination of multiple combat sports. Acute injuries in MMA are well known and have been broadly described. However, there is little knowledge about degenerative changes in the musculoskeletal system.

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Background: Wear debris is a major factor in aseptic loosening of total hip arthroplasty. Ultra high molecular weight polyethylene inlays are known for significant wear, and the following generation, highly cross-linked polyethylene (HCLPE), has shown promising in vitro and short-term in vivo results. This study aimed to investigate wear debris of HCLPE liners with ceramic heads after 9 years to reveal the in vivo wear kinetics of this common bearing combination.

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Osteoarthritis of the knee is one of the most commonly diagnosed joint ailments and responsible for increased rates of total knee arthroplasty surgeries worldwide. Whereas the surgical approach is able to diminish the perceived knee pain of concerned patients', the postoperative recovery is often accompanied by persistent skeletal muscle dysfunctions and atrophy, which is responsible for functional deficits for up to several years. Recent findings indicate that surgery induced adverse effects on skeletal muscles are largely associated with the use of pneumatic tourniquets, wherefore several studies try to reduce tourniquet use in orthopedic surgery.

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Purpose: Ischemic preconditioning (IPC) is known to reduce muscle damage induced by ischemia and reperfusion injury during surgery. Because of similarities between the pathophysiological formation of ischemia and reperfusion injury and eccentric exercise-induced muscle damage (EIMD), as characterized by an intracellular accumulation of Ca, an increased production of reactive oxygen species, and increased proinflammatory signaling, the purpose of the present study was to investigate whether IPC performed before eccentric exercise may also protect against EIMD.

Methods: Nineteen healthy men were matched to an eccentric-only (ECC; n = 9) or eccentric proceeded by IPC group (IPC + ECC; n = 10).

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Purpose: Advantages of tourniquet use in TKA include benefits for surgeons and patients, varying from a bloodless operation site to a reduced intervention time. The time under ischemia and the reperfusion period are crucial phases for affected soft-tissue, most commonly the extensor mechanism.

Case Reports: documented its impact on soft-tissue, ranging from necrotic muscle damage to systemic inflammation.

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Eccentric exercise training is effective for increasing muscle mass and strength, and improving insulin sensitivity and blood lipid profiles. However, potential muscle damage symptoms such as prolonged loss of muscle function and delayed onset of muscle soreness may restrict the use of eccentric exercise, especially in clinical populations. Therefore, strategies to reduce eccentric exercise-induced muscle damage (EIMD) are necessary, and an extensive number of scientific studies have tried to identify potential intervention modalities to perform eccentric exercises without adverse effects.

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Purpose: Rotational alignment of prosthetic components after total knee arthroplasty (TKA) is predominantly monitored with computer tomography (CT), for example by relating the anatomical transepicondylar axis (a-TEA) of the native femur to the posterior bicondylar axis of the prosthetic component (PBCA). The purpose of the present study was to portray a reliable, novel plain radiographic method that likewise enables the evaluation of rotational positioning of prosthetic components in TKA. Furthermore, it was intended to evaluate the prosthetic femoro-tibial functional behavior under loaded conditions.

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Purpose: To investigate the incidence of hyponatremia and its relationship to plasma copeptin, a surrogate marker for arginine vasopressin (AVP) during 28 days of high-volume rowing training.

Methods: Thirty rowers from the German junior national team (21 male) were studied during a training camp. Serum sodium ([Na(+)]), osmolality, and copeptin were measured before the beginning of the camp (day 0), and at days 7, 13, 18, 24, and 28.

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