Persistent T-wave inversion predicts myocardial damage after ST-elevation myocardial infarction.

Background: Persistent T-wave inversion (PTI) after ST-elevation myocardial infarction (STEMI) is associated with worse clinical outcome; however, the underlying mechanism between PTI and poor prognosis is incompletely understood. We sought to investigate the relationship between PTI and myocardial damage assessed by cardiac magnetic resonance (CMR) following STEMI.

Methods: In this prospective observational study, we included 142 consecutive revascularized STEMI patients.

Fibroblast growth factor 23 as novel biomarker for early risk stratification after ST-elevation myocardial infarction.

Objective: Adverse left ventricular (LV) remodelling is the major determinant of heart failure and mortality in survivors of ST-elevation myocardial infarction (STEMI). The role of fibroblast growth factor 23 (FGF-23) for LV remodelling prediction after STEMI is unknown. We therefore aimed to investigate the relation between circulating FGF-23 and LV remodelling following revascularised STEMI.