Doxycycline's effect on ocular angiogenesis: an in vivo analysis.

Purpose: To determine the in vivo effect of doxycycline on choroidal angiogenesis and pterygium growth by using a choroidal neovascular (CNV) murine model, a directed in vivo angiogenesis assay (DIVAA) and a pterygium murine model.

Design: Experimental study.

Participants: Three murine models were investigated with 4 mice minimum per group and 22 maximum per group.

Monovision with laser vision correction.

This article reviews the advantages and disadvantages of various techniques used to achieve monovision, with an emphasis placed on monovision with laser vision correction.

Microarray and protein analysis of human pterygium.

Purpose: Pterygium is a sunlight-related, ocular-surface lesion that can obscure vision. In order to identify specific genes that may play a role in pterygium pathogenesis, we analyzed the global gene expression profile of pterygium in relation to autologous conjunctiva.

Methods: Oligonucleotide microarray hybridization was used to compare the gene expression profile between human whole pterygium and autologous conjunctiva.