Publications by authors named "Conrad Maciejewski"
Purpose: The objective of this study is to review patients with chronic urinary symptoms and remote urethral sling surgery to determine the prevalence and predictors of obstruction.
Materials And Methods: A single-center retrospective review was performed on patients referred with chronic lower urinary tract symptoms (>6 months) and a history of urethral sling surgery. Obstruction was identified by urodynamics using the Blaivas criteria or fluoroscopy.
Introduction: The objectives of this study were to conduct a survey of intravesical botulinum toxin administration practices in Canada, to compare practices based on level of training, and to identify barriers to delivery.
Methods: A voluntary online survey was sent to all members of the Canadian Urological Association. Respondents who provide intravesical botulinum toxin were questioned on training, surgical volume, workup, technique, and followup practices.
Objective: To assess postoperative outcomes from the Adjustable TransObturator Male System (ATOMS) and identify factors influencing failure to achieve continence.
Patients And Methods: A multicentered analysis was performed on all patients treated for postprostatectomy incontinence using the third-generation ATOMS at 9 Canadian tertiary referral centers. The primary outcome was continence (defined as requiring ≤1 pad postoperatively for patients requiring ≥2 pads preoperatively and 0 pads for those requiring 1 pad preoperatively).
Flaps, grafts, and stages: The challenge of penile urethral stricture.
Can Urol Assoc J
December 2019
Purpose: We assessed the efficacy and safety profile of the ATOMS® (Adjustable Transobturator Male System) for post-prostatectomy incontinence in a multicenter North American setting.
Materials And Methods: We reviewed outcomes from 8 centers in men who underwent treatment of post-prostatectomy incontinence with an ATOMS. Primary study outcomes were pad changes and continence, defined as requiring 1.
Objective: To identify factors that predict patient satisfaction after urethroplasty by prospectively examining patient-reported quality of life scores using 3 validated instruments.
Methods: A 3-part prospective survey consisting of the International Prostate Symptom Score (IPSS), the International Index of Erectile Function (IIEF) score, and a urethroplasty quality of life survey was completed by patients who underwent urethroplasty preoperatively and at 6 months postoperatively. The quality of life score included questions on genitourinary pain, urinary tract infection (UTI), postvoid dribbling, chordee, shortening, overall satisfaction, and overall health.
Accurate imaging of urethral strictures is critical for preoperative staging and planning of reconstruction. The current gold standard, retrograde urethrography (RUG), allows for accurate diagnosis, staging, and delineation of urethral strictures, and remains a cornerstone in the management of urethral stricture disease. In complex situations, the RUG can be combined with voiding cystourethrogram (VCUG) in order to better visualize the posterior urethra or complex distraction defects.
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- Bladder deterioration from partial outlet obstruction (pBOO) is common and has serious health implications, and the study aimed to see if specific oral medications can alter this condition.
- Female rats with surgically induced pBOO were treated with various medications, including oxybutynin and tadalafil, to evaluate their effects on bladder health over 16 weeks, assessing factors like bladder capacity and collagen content.
- Results showed that both oxybutynin and tadalafil improved bladder function compared to controls, with tadalafil also demonstrating an antifibrotic effect by reducing collagen content, highlighting the potential for these medications to alter the harmful effects of pBOO in clinical settings.
Purpose: Partial bladder outlet obstruction has been shown in a rat model to progress from inflammation to hypertrophy to fibrosis. Small leucine-rich proteoglycans are extracellular matrix components associated with collagen fibrillogenesis and resultant scar formation. Two such critical small leucine-rich proteoglycans are decorin and biglycan.
View Article and Find Full Text PDFPurpose: To quantify the accuracy of magnetic resonance imaging (MRI) measurement of change in cartilage volume due to thin linear excisions, simulating arthritic cartilage losses, by comparison with laboratory volume measurements in an ex vivo porcine model.
Materials And Methods: We scanned 15 porcine patellae by T1-weighted spoiled gradient echo (SPGR) MRI at baseline and after excision of up to three thin layers of articular cartilage. Excised fragment volume was determined from density and weight.