Frequency of serrated polyposis syndrome recognition by community endoscopists.

Some data indicate serrated polyposis syndrome (SPS) is underdiagnosed. We determined the frequency of SPS diagnosis by community endoscopists prior to referral to a tertiary center. We performed a retrospective analysis of a prospectively collected database of SPS patients at a tertiary academic hospital.

Impact of changing diagnostic criteria on the diagnosis of serrated polyposis syndrome.

The World Health Organization criteria for serrated polyposis syndrome (SPS) were established in 2010 and modified in 2019. Neither set of criteria have been validated against genetic markers or proven to be the optimal criteria for defining colorectal cancer risk in patients with serrated colorectal lesions. In this study, we sought to gain insight into how frequently the change in SPS criteria in 2019 impacted the diagnosis of SPS.

Frequency and nature of endoscopic and pathologic errors leading to referral for endoscopic resection to a tertiary center.

We anecdotally encounter cases where referring endoscopists made errors in endoscopic interpretation of a colorectal lesion, sometimes combined with pathology errors at the referring centers, resulting in referral to our center for endoscopic resection. In this paper, we describe the frequency and nature of endoscopic and pathology errors leading to consultation for endoscopic resection. Review of 760 consecutive referrals to our center over a 26-month interval.

Adverse events and residual lesion rate after cold endoscopic mucosal resection of serrated lesions ≥10 mm.

Background And Aims: Cold EMR is being increasingly used for large serrated lesions. We sought to measure residual lesion rates and adverse events after cold EMR of large serrated lesions.

Methods: In a single academic center, we retrospectively examined a database of serrated class lesions ≥10 mm removed with cold EMR for safety and efficacy.

Room temperature water infusion during colonoscopy insertion induces rectosigmoid colon mucus production.

Background: Water filling during colonoscopy improves several colonoscopy outcomes. We evaluated an anecdotal observation that room temperature water filling during colonoscope insertion results in mucus production in the left colon, which may impair mucosal visualization during withdrawal.

Methods: We performed 55 colonoscopies with either water or saline filling during insertion, and video recorded the examinations.

Impact of water filling on terminal ileum intubation with a distal-tip mucosal exposure device.

Background And Aims: Endocuff improves detection at colonoscopy but seems to impede terminal ileal (TI) intubation. We assessed the impact of Endocuff Vision (EV) on TI intubation using adult or pediatric colonoscopes and evaluated whether filling the cecum with gas versus water affected the impact of EV on TI intubation.

Methods: Using a prospectively recorded quality control database, we explored the impact of EV on TI intubation in ≤1 minute.

A comparison of 2 distal attachment mucosal exposure devices: a noninferiority randomized controlled trial.

Background And Aims: Endocuff (Arc Medical Design, Leeds, UK) and Endocuff Vision (Arc Medical Design, Leeds, UK) are effective mucosal exposure devices for improving polyp detection during colonoscopy. AmplifEYE (Medivators Inc, Minneapolis, Minn, USA) is a device that appears similar to the Endocuff devices but has received minimal clinical testing.

Methods: We performed a randomized controlled clinical trial using a noninferiority design to compare Endocuff Vision with AmplifEYE.

Impact of a ring-fitted cap on insertion time and adenoma detection: a randomized controlled trial.

Background And Aims: Devices for flattening colon folds can improve polyp detection at colonoscopy. However, there are few data on the endoscopic ring-fitted cap (EndoRings; EndoAid, Caesarea, Israel). We sought to compare adenoma detection with EndoRings with that of standard high-definition colonoscopy.

SIC-8000 versus hetastarch as a submucosal injection fluid for EMR: a randomized controlled trial.

Background And Aims: Viscous solutions provide a superior submucosal cushion for EMR. SIC-8000 (Eleview; Aries Pharmaceuticals, La Jolla, Calif) is a commercially available U.S.