3DVar sectoral emission inversion based on source apportionment and machine learning.

Air quality models are increasingly important in air pollution forecasting and control. Sectoral emissions significantly impact the accuracy of air quality models and source apportionment. This paper studied the 3DVar (three-dimensional variational) emission inversion method, which is based on machine learning, and then expanded it to sectoral emission inversion combined with source apportionment.

Mapping high-resolution energy consumption CO emissions in China by integrating nighttime lights and point source locations.

High-resolution CO emission inventories are essential to accurately assess spatiotemporal patterns of carbon emissions, analyze factors affecting carbon emissions, and develop sound emission reduction policies. The top-down approach is often used to map CO emissions from energy consumption due to its simplicity. However, the spatial proxy variables commonly used in this method, such as nighttime light (NL), land use, and population, are difficult to reflect the spatial distribution of CO emissions from large point sources.

[Correlation between macrophage chemotaxis and disease severity in patients with knee osteoarthritis].

Objective: To investigate the enhancement of macrophage chemotaxis in patients with knee osteoarthritis (KOA) and its correlation with the disease severity.

Methods: Eighty patients with KOA admitted from July 2019 to June 2022 were enrolled as the observation group and divided into 29 cases of moderate group, 30 cases of severe group and 21 cases of extremely severe group. At the same time, 30 healthy subjects were included as the control group.

The underlying mechanisms of PM and O synergistic pollution in East China: Photochemical and heterogeneous interactions.

The rapid development of Chinese cities is accompanied by air pollution. Although the implementation of air pollution control strategies in recent years has alleviated PM pollution, O pollution and the synergistic pollution of PM and O have become more serious. To understand the underlying chemical interaction mechanisms between PM and O, we applied the modified Weather Research and Forecasting model with Chemistry (WRF-Chem) to study the effects of aerosol-photolysis feedback and heterogeneous reactions on the two pollutants and revealed the contribution of different mechanisms in different seasons and regions in Yangtze River Delta (YRD) in eastern China.

Study on the variation of air pollutant concentration and its formation mechanism during the COVID-19 period in Wuhan.

To prevent the spread of COVID-19 (2019 novel coronavirus), from January 23 to April 8 in 2020, the highest Class 1 Response was ordered in Wuhan, requiring all residents to stay at home unless absolutely necessary. This action was implemented to cut down all unnecessary human activities, including industry, agriculture and transportation. Reducing these activities to a very low level during these hard times meant that some unprecedented naturally occurring measures of controlling emissions were executed.

[Component Characteristics and Source Appointment of Volatile Organic Compounds in Lianyungang City].

Volatile organic compounds (VOCs) are important precursors of ozone and particulate matter; thus, their impacts on air quality are particularly significant. To study the composition characteristics and sources of VOCs in Lianyungang City, four national control sites were selected to conduct VOCs sampling and analysis on typical days in spring, summer, and autumn. Concentrations of VOCs, the effects of different components of VOCs on ozone formation were quantified, and the sources of VOCs were analyzed using the Positive Matrix Factorization model.

Atorvastatin combined with poly-unsaturated fatty acid confers better improvement of dyslipidemia and endothelium function.

Background: Atorvastatin and poly-unsaturated fatty acid (PUFA) are beneficial for lipid-modification, whether atorvastatin plus PUFA could confer better improvement on dyslipidemia and endothelium function is unknown.

Methods: Dyslipidemia model of 40 rabbits were produced with atherogenic diet, and thereafter saline, atorvastatin, PUFA, or atorvastatin plus PUFA were prescribed for 1 week. Ten rabbits given normal diet served as the sham group.

Effects of calcitriol on bone mineral density in patients treated with esomeprazole.

Context: Proton pump inhibitor (PPI) increases the risk of decrease in bone mineral density (BMD). However, whether calcitrol improves this situation is unknown.

Objective: The current study investigates the effects of calcitriol on BMD in patients with esomeprazole therapy.

Metformin enhances nitric oxide production and diminishes Rho kinase activity in rats with hyperlipidemia.

Background: Rho kinase over-activation is associated with nitric oxide (NO) reduction and atherosclerosis. Metformin is favorable for endothelial function improvement and cardiovascular outcomes. Whether cardio-protective effect of metformin is associated with Rho kinase activity is unknown.

Synergistic effects of colchicine combined with atorvastatin in rats with hyperlipidemia.

Background: Inflammation and endothelial dysfunction is implicated in the atherosclerosis initiation and progression in the setting of hyperlipidemia. Colchicine is a potent anti-inflammatory agent and whether colchicine combined with atorvastatin has synergistic effects on inflammation amelioration and endothelial function improvement is unknown.

Methods: Hyperlipidemic rat model was produced by high-fat and high-cholesterol diet for 6 weeks.

[Relationship of serum iron and ferritin with the indicators for hepatic fibrosis].

Objective: To study the relationship of serum iron and ferritin with the indicators for hepatic fibrosis and hepatic iron overload.

Methods: Liver tissue specimens were obtained from 41 patients with benign (16) or malignant (25) liver diseases by 1 second liver biopsy, and routine microscopic examination was performed after haematoxylin-eosin (HE) and Perl's Prussian staining. Atomic absorption spectrum, radioimmunoassay and enzyme-linked immunosorbent assay were respectively employed to examine the serum levels of iron, ferritin, hyaluronic acid, laminin, human procollagen type , and collagen type .

[Clinical value of carbohydrate antigen 50 and carbohydrate antigen 242 in the diagnosis of colorectal carcinoma].

Objective: Carbohydrate antigen 50 (CA50) and 242 (CA242), recently recognized as serum tumor markers, are studied for their value in the diagnosis of the colorectal carcinoma.

Methods: This study included 48 patients with benign bowel disease and 71 patients with colorectal carcinoma, whose serum CA50 and CA242 levels were measured by immunoradiometric assay.

Results: The total positivity of CA50 and CA242 in colorectal carcinoma cases were 69.

[Iron overload and liver diseases].

The awareness of the harm of deficiency in iron, an essential trace elements for the growth of almost all types of biological cells, has long been established. Iron overload, however, is not equally well documented to be related to certain diseases. In this article the author reviews the association of iron overload with some frequent hepatic diseases.