Publications by authors named "Congting Hu"
Previous studies have indicated an association between vitamin D and thyroid- and parathyroid-related diseases. However, it remains unclear whether it is a cause of the disease, a side effect of treatment or a consequence of the disease. The Mendelian randomisation (MR) study strengthens the causal inference by controlling for non-heritable environmental confounders and reverse causation.
View Article and Find Full Text PDFObjective: Previous studies have investigated the association between diabetes medications and thyroid cancer, but the results have not been conclusive. This study used a Mendelian randomization approach to investigate the causal relationship between diabetes medications and thyroid cancer (TC).
Methods: Exposures were six major diabetes medications target, while outcomes were TC and its differentiated forms, including papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC).
Article Synopsis
- The study aimed to evaluate the impact of pharmacist interventions on patients with type-2 diabetes by reviewing existing literature.
- A systematic search across six databases included 35 studies with 4,827 patients, revealing that pharmacist interventions improved several health metrics such as HbA1c, LDL-C, and blood pressure while enhancing medication adherence.
- However, the interventions did not show significant improvement in HDL-C, total cholesterol, or triglycerides.
Background And Objective: There is a considerable survival benefit of alpelisib in patients with PIK3CA-mutated, hormone receptor-positive and human epidermal growth factor receptor 2-negative advanced breast cancer (HR+/HER2- ABC), yet the financial burden may limit its use. Therefore, this study evaluated the cost-effectiveness of alpelisib plus fulvestrant in patients with PIK3CA-mutated, HR+/HER2- ABC in the USA.
Methods: A Markov model was constructed to simulate the progression of PIK3CA-mutated, HR+/HER2- ABC.
Lipid metabolism may be involved in the development of endocrine drug resistance in ER-positive (ER+) breast cancer (BC). This study aimed to investigate the relationship between serum lipid levels, risk stratification of dyslipidemia, and endocrine resistance. We collected the data from 166 ER + breast cancer patients who received endocrine therapy (ET).
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